Exam 3 Misc. Flashcards
Main point when treating patients with cardiac drugs
adequate cardiac output
Priority nursing diagnosis for cardiac drugs
ineffective tissue perfusion
Afterload
pressure the heart has to work against to get the blood out
- the higher the pressure, the less blood the L ventricle will get out
- causes decreased CO
Preload
amount of blood that gets to the right atrium from the superior vena cava
- increased preload= increased CO
- decreased preload= decreased CO
chronotropy
- “chrono” means time
- drugs effecting heart rate
- positive chronotropy means we make it faster
- negative chronotropy means we slow it down
Inotropy
- How forcefully it contracts
- Decrease in force is a decrease in CO
Dromotropy
- Speed of conduction
- increase in conduction speed= increase in HR and vice versa
What is the risk of an increased afterload?
Clots will form because too much blood is sitting
Drug that everyone is on in hospitals because of immobility
heparin
Heparin antidote
protamine sulfate
Normal PT values
10-14 sec
Normal PTT values
20-45 sec., Max 112 sec
Difference between heparin and enoxaparin
- Heparin is used to treat the problem, enoxaparine is used to prevent it
- enoxaparine is safer
Antidote to warfarin
Vitamin K
Blood tests for heparin and enoxaparin
PT and PTT
Blood tests for warfarin
INR
Problems with warfarin
dangerous drug, lots of toxicity and treatment failure
What should people take instead of ferrous sulfate and why?
ferrous gluconate, its much easier on the stomach
Patient teaching for ferrous sulfate/ iron
Take for 6 months- this is hot much time it takes for the body to store enough iron to meed daily requirements on its own
Vitamin B12 is used for…
Pernicious anemia
Sickle Cell anemia is common in which group
African Americans
Antianemic drug to treat Sickle Cell anemia
hydroxyurea - antineoplastic that increases fetal RBCs
Vasopressers
Nitroprusside and Hydralazine
-increase BP
First choice antihypertensives
ACE Inhibitors
Expected side effect with ACE inhibitors
-cough
ACE enzymes are also in the lungs so if we inhibit them, we get a cough
What do you do if ACE inhibitors cause cough?
put them on an ARB
How does high cholesterol affect afterload?
increases it
-too many lipids make thick blood and increase afterload or stick to vessels making diameter thinner
high cholesterol
> 200
Side effect of statins
Rhabdomyolysis- muscle tissue breaks up and all the contents of muscle cells spill out into systemic system
- lethal
- myoglobin would be present in systemic system
Normal triglycerides
150
Normal digoxin level
between 0.8 and 2
Digoxin’s effect on the tropys
negative chronotropy, positive inotropy, negative dromotropy
s/s of dig toxicity
vision problems, confusion, vomiting, diarrhea
digoxin antidote
Dig Immune Fab- binds to digoxin and doesn’t allow it to do its job
anti-arrhythmics and tropys
all anti-arrythmics decrease all three: negative chrono-, ino- and dromotropy
Side effects of nitrates
raging headaches
leading cause of death in the western world
CAD
Functions of good lipids
need lipids for steroids, hormones, helps us use vitamin D, involved in absorption of fat soluble vitamins
Desired cholesterol values
Total Chol
What do we give when people can’t tolerate statins
bile acid sequestrants because they bypass the liver and metabolize in the stomach
Problem with bile acid sequestrants
- causes decreased fat-soluble vitamin absorption
- GI distress
Can you control cholesterol with diet?
Kind of, but our bodies still make it, so its also genetic
When should statins be given?
at night- that’s when our bodies make cholesterol
s/s of Rhabdo
- bloody urine, muscle pain, weakness, kidney failure
- labs: urinalysis, BUN, creatinine, I&O, liver enzymes
Cholesterol absorption inhibitors
- decreases absorption in the brush border
- used with statins when statins aren’t working
- works in the intestines so its good for people with liver probs
Fibrates
-triglyceride and lipoprotein destruction