Exam 3: Minerals Flashcards
Minerals are ________ elements that are required for the maintenance of good health and production
INORGANIC
examples of macro minerals
Ca
P
Mg
Na
Cl
K
S
examples of micro minerals
Fe
Mn
Cu
I
Zn
Cr
Co
Se
what minerals are not normally supplemented in diets because levels in feed ingredients are sufficient
Mg and S
what minerals are considered electrolytes
Na
Cl
K
Are minerals the only class of nutrients that are inorganic, yes or no
yes
functions of mineral elements
structure
cofactors for enzymes
constituents of essential components in body
constituents of body fluids
structural mineral element examples
teeth and bone
charge on metal ions can aid enzymes
cofactors
examples of constituents of essential components in body
IRON in hemoglobin
IODINE in thyroxine
COBALT in vitamin B12
SULFUR in methionine and biotin
MOLYBDENUM in xanthin oxidase
difference between coenzyme and prosthetic group
coenzyme: non-permanent relationship, organic non-protein compound
prosthetic group: permanent relationship of enzyme and nonprotein organic compound (vitamin)
examples of constituents of body fluids (blood, interstitial fluid, intracellular fluid)
transmission of nerve impulses
maintain normal blood pH by acting as buffers
maintain osmotic pressure
all animals are subjected to mineral deficiencies which may be caused by
suboptimal amount of feed
imbalance of another mineral which decreases the absorption
any condition which increases the rate of passage of elements through the gut or body (diarrhea)
a metabolic antagonist which causes the animal to require more dietary mineral to overcome
Excretion routes vary (list possible routes)
almost entirely feces
some urine (electrolytes)
some both routes
some lost in sweat (like Na)
Iron (Fe) may be lost due to blood loss
Iron (Fe) may be lost due to blood loss. What are some examples where blood is lost
wound
disease
menstrual cycles
many minerals are involved in the process called
chelation
A chelating agent binds to a mineral to varying degrees and general has the effect of isolating the mineral from interactions with other compounds
mineral attaches to poison/metal and drags it out of the body
chelation
nutritional significance of chelation
may bind trace elements in the diet and release them at sites where they’re needed
prevents other interactions during digestion
medical functions of chelation
remove certain isotopes or poisons from body to have them excreted
example: viruses/bacteria, lead toxicity
natural chelators
Hemoglobin to iron
vitamin b12 to Cobalt
synthetic chelators
EDTA
other than being a synthetic chelator, what function does EDTA have
acts as a anticoagulant bu sequestering ca++ ions for clotting
other than being a synthetic chelator, what function does EDTA have
acts as an anticoagulant by sequestering ca++ ions for clotting
in many respects _____________ are integrated in metabolism-compose over _______% of body minerals; are quantitatively the 2 most important
calcium and phosphorus
70%
adequate Ca and P nutrition depends on 3 factors
a sufficient supply of Ca and P
the suitable ratio between the two, 1:1 or 2:1
presence of vitamin D
Increase in vitamin D causes an increase in
utilization of Ca and P
___% of Ca and ___% of P are in bones and teeth (structural components)
99%
80%
Ca is necessary for _______________ mechanism along with vitamin D and K
blood clotting
what do Ca and P form that is extremely hard and difficult to solubilize
hydroxy apatite crystals
Ca++ interacts with other minerals to control and regulate
muscles and nerve reactions
Ca++ deficiency can lead to
tetany or continuous contraction
excess Ca++ can impair _______ function so that cardiac or respiratory _____ may result
muscle
failure
Calcium is an osmoregulator meaning
it helps regulate osmotic pressure of cellular fluids in the body
calcium helps maintain ___________ of the body fluids
acid-base equilibirum
pancreatic lipase, succinic dehydrogenase, ATPase are examples of
enzyme activators of calcium
calcium absorption occurs primarily in
proximal portion of the gut (upper section of midgut)
calcium absorption depends on
its solubility at point of contact with absorbing membranes
factors that help/contribute to Ca++ absorption
acid conditions help keep Ca in the solution
adequate vitamin D
low phytic acid
low oxalic acid
low P levels
estrogen
age
high phytic acid, does what to absorption
decreases
excess P or Ca levels can do what to absorption
decrease
Increase age does what to absorption
decrease
estrogen does what to absorption and storage of calcium
increase
route for undigested and unabsorbed Ca and P as well as endogenous Ca and P
Feces
is apparent digestibility useful for determining the usefulness of dietary Ca and P sources
NO
a decrease in serum calcium causes what
increase in parathyroid hormone
release Ca++ from bone
increase in serum calcium causes what
increase in calcitonin
decrease blood Ca
when serum Ca decreases the parathyroid (PTA)does what
Bones: increase osteoclast
Kidney: increase Ca in urine reabsorption
Intestine (midgut): increase rate of Ca absorption from diet (upregulate expression of callbridin)
types of bones cells
osteoclast
osteoblast
calcium deficiency leads to
reduced growth, especially in bone
hyper irritability
tetany
poor repro performance
rickets (young animals)
beading of ribs is caused by
calcium or phosphorus deficiency
rickets vs osteomalacia
Rickets: young animals; bones dont calcify properly, bones are weak and can fracture
Osteomalacia: adult bone; softening of bone due to decrease in mineral content
weakness, fractures, deformity
possible causes of osteomalacia
excess PTH
low blood Ca or P
pregnancy or lactation
______and ______ are most likely to be deficient in Ca++ due to their rapid growth and diets, lack exposure to sun (vitamin D)
pigs and poultry
grains and protein concentrates are lower in ____ that roughages
Ca
______% of ___ is in bone and is associated with Ca
80%
Phorphorus
most of P is found in
RBC
inorganic P is found in
plasma
_______ play an important role in maintaining phosphorus balance
kidneys