Exam 3 Antiplatelets/Anticoagulants

Question 1

When would a pt. need to be on an anticoagulant?

Answer 1

After bedrest, after surgery, DVT/PE/stroke/MI

Question 2

What puts pt’s at risk for DVT and PE?

Answer 2

Hypercoagulation, venous stasis, endothelial damage

Question 3

Antiplatelet and Anitocagulants

Answer 3

PREVENT new clots (Inhibiting factor Xa or thrombin will lead to anticoagulation or antiplatelet)

Question 4

Thrombolytics

Answer 4

Break up clots (Activate plasminogen or plasmin will break up)

Question 5

Which labs measure anticoagulation/anti-platelet??

Answer 5

APTT should be 30-40.
If someone is on an anticoagulant, we want their APTT to be increased 2-2x times… for ex. you want 60-80 on APTT. SOMETIMES, you may see it even higher.

Question 6

Because PT varies by lab,

Answer 6

People use an INR; the international value.

Question 7

What is a heparin bridge

Answer 7

Will be on heparin 12hr before surgery.

Question 8

What is Lovenox?

Answer 8

Low molecular weight Heparin; given short term at home or hospital but no APTT required.