exam 2 chapter 12 Flashcards
schizophrenia
tear or split (schizo) in one’s intellect (phren) and emotional stability; conceptualized as a brain disease with genetic/environmental factors at play; onset typically during young adulthood; about 1% world prevalence; “psychosis”
Bleuler’s fundamental symptoms of schizophrenia (6)
disturbances of association (illogical thought process), disturbances of affect (i.e. inappropriateness), ambivalends (conflicting thoughts and emotions), autism (detachment from social life with inner preoccupation), abulia (lack of drive or motivation), dementia (irreversible change in personality)
Bleuler’s “accessory symptoms” (5)
delusions, hallucinations, movement disturbances, somatic symptoms, manic and melancholic states
Kurt Schneider “first rank symptoms” (7)
thought echoing or audible thoughts, thought broadcasting, thought intrusion, thought withdrawal, somatic hallucinations, passivity feelings, delusional perception
social processing deficits (7)
solving social problems, processing of emotions, social perception, attribution of events, theory of mind (perspective taking), blunted and more negative affect, out of context affect
cognitive deficits (7)
processing speed, attention/vigilance, working memory, verbal learning, visual learning, reasoning and problem solving, social cognition
DSM-5 conceptualization
two or more: hallucinations, delusions, disorganized speech, grossly disorganized or catatonic behavior, negative symptoms
also: significant social dysfunction; no relation to mood or other disorder, substance or medical condition; Dx only given for people with Dx of autism if hallucinations and/or delusions are prominent
genetics
inherited vulnerability
neurotransmitters
dopamine: antipsychotic medication exerts influence by diminishing dopaminergic activity in the brain, especially the subcortical portions