exam 2 Flashcards
1
Q
where does t cell development occur
A
thymus
2
Q
where is the thymus
A
above the heart
3
Q
goal of thymus
A
negative and positive select
4
Q
the thymus positively select for
A
T cells that interact with self MHC protein (survivial)
5
Q
the thymus negatively select for
A
T cells that bind self antigen (dearth)
6
Q
the master regulator of T cell developement
A
Notch1
7
Q
double negative makes
A
gamma delta t cells
lack cd4 and cd8
8
Q
double positive makes
A
alpha beta T cells
expresses cd4 and cd8
9
Q
single positive makes
A
cd4 or cd8
10
Q
A
