Ex2 L3 ANS Flashcards

1
Q

Parasympathetic and sympathetic NS are part of which system

A

Efferent

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2
Q

Under subconscious control of ANS

A

Smooth muscle, cardiac muscle, glands

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3
Q

Which system should be in control most of time?

A

Parasympathetic NS

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4
Q

Sensory arm of ANS

A

Autonomic afferent fibers

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5
Q

Target cell of ANS

A

Smooth muscle, cardiac muscle, glands

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6
Q

Reference point of ANS

A

Ganglion

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7
Q

First synapse in ANS

A

At ganglion

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8
Q

Second synapse in ANS

A

Target cells

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9
Q

PNS maintains baseline function how

A

Highly adapted for very discrete stimulation of one organ vs another depending on needs at the time

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10
Q

Anatomically adapted

A

Sympathetic NS

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11
Q

Sympathetic nervous system functions how

A

Global activation

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12
Q

How are PNS/SNS different?

A
PNS = discrete
SNS = global
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13
Q

Sympathetic chain ganglia

A

One on each side of spinal cord

Most of ganglionic synapse occurs here

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14
Q

Peripheral ganglia

A

Celiac ganglia

Hypogastric plexus

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15
Q

Preganglionic cells of sympathetic chain ganglia located

A

Cell bodies in spinal cord

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16
Q

Preganglionic sympathetic cells are located

A

Lateral horn of spinal cord

17
Q

One exception to 2 synapse, 2 cell rule

A

Adrenal medulla

18
Q

Endocrine arm of sympathetic nervous system

A

Adrenal medulla

19
Q

Adrenal medulla pathway

A

One cell, one synapse

Preganglionic cell —> out of spinal cord —> moves thru celiac ganglion —> makes direct contact on adrenal medulla

20
Q

Effect of adrenal medulla in relation to SNS

A

Longer effects (hormones circulating in system)

21
Q

Most important PNS nerve

A

Vagus nerve (CN X)

22
Q

2 NT critical for ANS

A

ACh, Norepinephrine

23
Q

First synapse of ANS

A

Same for SNS/PNS: ACh binds to nicotinic receptor

24
Q

Where do PNS/SNS differ?

A

2nd synapse (between post/target cell)

25
Q

PNS binds to ____ on 2nd synapse

A

ACh binds to muscarinic receptor

26
Q

SNS releases _____ which binds to ____ on 2nd synapse

A

Neurotransmitter: Norepinephrine
Receptor: A1, B1, B2

27
Q

B1 receptors are located

A

Heart

28
Q

B2 receptors

A

Prominently Smooth muscle of airways (Lungs)

Greater affinity for epi > Norepi

29
Q

B2 receptors have higher affinity for

A

Epinephrine (released from adrenal medulla)

30
Q

Albuterol is most similar to

A

Epinephrine

31
Q

Alpha 1 receptors stimulated

A

Sodium channels open
Depolarizes
Muscle cell - contraction

32
Q

Beta 2 receptors stimulated

A

Opens potassium channels
Hyperpolarizes
Muscle: relaxation

33
Q

Kidneys are only innervated by

A

Sympathetic nervous system

34
Q

Most organs are innervated by

A

Both PNS/SNS

Antagonistic effect

35
Q

Control of autonomic fxn

A

Brainstem, hypothalamus