Essays 71-80 Flashcards
canine testicular tumours
incidence
90% of all cancers in male repro tract
intact male
>10yrs
types of canine testicular tumours
seminomas
sertoli cell tumours
leydig cell tumours
risk factors of canine testicular tumours
cryptorchidism
age
carinogen exposure
breed = german shepherd, weimaraner, shetland, collie
metastasis of canine testicular tumours
rarely
diagnosis of canine testicular tumours
rectal palp
physical exam
xray, mri, ct
CBC, biochem
FNA
biomarkers
biomarkers of canine testicular tumours
AMH
inhibins
IGF
therapy of canine testicular tumours
bilateral orchiectomy
exploratory laparotomy
sertoli cell tumour
8-16% of testiculr tumours
rarely secrete estrogen, testosterone
often cycstic
signs = lethargy
leydig cell tumours
30-50% of testicular tumours
rarely estrogen, testosterone
rare metastases
often cystic
how common are uteral tumours
not v common
dog uteral tumours names
leiomyoma / sarcoma
fibrom / sarcoma
hemangioma
lipoma
lymphoma
angio - lipo - leiomyoma
cats uteral tumours names
adenocarcinoma
adenosarcoma
leiomyoma / sarcoma
fibroma / sarcoma
lymphoma
hemangioma
lipoma
scc
clinical signs of uteral tumours
abdominal distension
abnormal estrus cycle
vaginal discharge
stanguria
pyometra
pu/pd
vommitting - weight loss
therapy of uteral tumours
ovarian hysterectomy
dogs vaginal tumours names
leiomyoma / sarcoma
fibroleiomyoma
fibroma
polyps
lipoma
canine clitoral carcinoma
which vaginal tumours is hormone dependant
leiomyoma
diagnosis of vaginal tumours
vaginal and rectal palp
vaginoscopic examination
cytology
histopath
hypophyseal tumours
pituitary corticotroph tumour
pituitary somatotroph tumour
pituitary corticotroph tumour
incidence
most common cause of hyperadrenocoricism
pituitary corticotroph tumour
diagnosis
mri
pituitary corticotroph tumour
therapy
chemo - trilostane, milostane, selegiline
hypophysectomy
radiotherapy
pituitary somatotroph tumour
common in older cats
from chronic excessive GH secretion or adenohypophysis
male > female
pituitary somatotroph tumour
diagnosis
signs - neurological, lethargy, lameness, cardaic diseases
CT, MRI
types of adrenal gland tumours
carcinomas > adenoma > hyperplastic lesions
adrenal gland tumours characteristics
occur in cortex > medulla
can cause hyperadrenocorticism and gcc secretion
adrenal gland tumours in dogs
adenoma <2cm
carcinoma >2cm
adrenal gland tumours in dogs
signs
lethargy
anorexia
PU/PD
hypokalemia
metabolic alkalosis
adrenal gland tumours in dogs
therapy
surgery
mitotane, trilostane
adrenal gland tumours in cats
more of a functional tumour than in dogs
causing hyperaldosteronism
adrenal gland tumours in cats
clinical signs
atrial hypertension
hypokalemia
metabolik alkalosis
renal disease
adrenal gland tumours in cats
therapy
surgery
k supplementation
anytihypertensives
spirolactone
thyroid tumours in dog
genetic
siberian uskeys
golden retrivers
10-15yrs
thyroid tumours in dog
characteristics
loft sided
unilobed
carcinoma or adenocarcinoma
vascular
metastases to ln, lungs
thyroid tumours in dog
diagnosis
CT, US
dysphagia
horners
voice change
layrngeal paralsis
thyroid tumours in dog
therapy
surgery
radiotherapy
thyroid tumours in cat
environmental factors
iodine content of canned food
indoor
cat litter
flea control products
thyroid tumours in cat
characteristics
adeoma
both lobes
thyroid tumours in cat
sigsn
weight loss
hyperactive
vomitting
diarrhoea
PUPD
tachycardia, arrhythmia
thyroid tumours in cat
therapy
methimazole
carbimazole
ipodate
iodine restricted diet
thyroidectomy
radioactive iodine
canine osteosarcoma
incidence
large breeds
rottweilers
middle ages/ older
male > female
canine osteosarcoma
sites
legs > trunk
fl > hl
long bones
elbow far, knee close
canine osteosarcoma
clinical signs
pain
lameness
bone swelling
muscular atrophy
patholofical fractures
hypertropic osteopathy
resp signs due to metastases
canine osteosarcoma
xray signs
sharp borders
matrix calcification
new bone formation
swelling
pathological fracutres
canine osteosarcoma
diagnosis
history
ALP
haematology
kidney & liver labs
xray, ct, scintigraphy
FNA
biopsy - rare
canine osteosarcoma
therapy
palliative pain killers - piroxicam, gcc,
amputation - gold standard
limb sparing techniques -cisplatin implant
chemo - cisplatin, carboplatin, doxorubin
immunotherapy - IL2, losartan
radiotherapy