Equine Genetics Diseases

Question 1

name one of the examples on the 5 panel test?

Answer 1

Glycogen branching enzyme deficiency
hereditary equine regional dermal asthenia
hyperkalemic periodic paralysis
malignant hyperthermia
polysaccharide storage myopathy

Question 2

name the 6 or 7 panel tests?

Answer 2

myosin-heavy chain myopathy
overo lethal white syndrome

Question 3

GBED is what type of disease?

Answer 3

autosomal recessive (2 copies to be affected)

Question 4

symptoms of GBED?

Answer 4

abortions, stillbirths, weakness, hypothermia, sudden death

Question 5

result of GBED?

Answer 5

fatal

Question 6

HERDA is what type of disease?

Answer 6

autosomal recessive

Question 7

what stallion does HERDA trace back to?

Answer 7

95% to Poco Bueno

Question 8

symptoms of HERDA?

Answer 8

skin lesions, wrinkling of skin, hematomas, slow healing

Question 9

result of HERDA

Answer 9

death, gets worse over time

Question 10

name a famous stallion with a copy of HERDA?

Answer 10

metallic cat

Question 11

what type if disease is HYPP?

Answer 11

autosomal dominant (1 or 2 copies to be affected)

Question 12

HYPP traces back to who?

Answer 12

Impressive

Question 13

symptoms of HYPP?

Answer 13

paralysis, weakness, muscle tremors

Question 14

considerations and results of HYPP?

Answer 14

diet, exercise, not fatal if managed right

Question 15

PSSM1 is what type of disease?

Answer 15

autosomal dominant

Question 16

what horses commonly have PSSM1?

Answer 16

stock-type, drafts, TWH, morgans

Question 17

symptoms of PSSM1?

Answer 17

muscle pain, weakness, sweating, hard to move

Question 18

result of PSSM1?

Answer 18

okay if managed, high fat low starch diet

Question 19

MH is what type of disease?

Answer 19

autosomal dominant

Question 20

symptoms of MH?

Answer 20

hypermetabolic state, fever, sweating, breakdown of muscle tissue

Question 21

triggers of MH?

Answer 21

hallithane anesthesia, stress

Question 22

MYHM is a mutation in what gene?

Answer 22

MHY1

Question 23

MYHM is what type of disease?

Answer 23

autosomal, only some show this with 2 copies

Question 24

symptoms of MYHM?

Answer 24

tying up, muscle wasting, increase in serum creatine kinase

Question 25

horses with MYHM can lose ___% of muscle mass in ___ hours?

Answer 25

40% in 48 hours

Question 26

triggers of MYHM?

Answer 26

strangles bacteria, respiratory virus and vaccines, stress

Question 27

result of MYHM?

Answer 27

50% recurrent episodes, regain muscle mass in 2-3 months

Question 28

what type of disease of OLWS?

Answer 28

incomplete dominant (2 copies to be lethal)

Question 29

symptoms of OLWS?

Answer 29

white coat at birth, intestinal tract issues

Question 30

horses common to see OLWS in?

Answer 30

frame overo, paints, some TBs, QHs and minis