EPIvax

Question 1

Examples of live vaccines

Answer 1

BCG; Measles; MMR; Varicella; Rotavirus; Intranasal Influenza; oral Typhoid

Question 2

indications of passive immunization

Answer 2

congenital/acquired B cell defects; time not permitting adequate protection by active immunization alone(hepB; measles; rabies; varicella); high risk of complications(measles and var in leukemic child); disease is already present and antibody may aid in suppressing toxin effects(tet) or inflammatory response(kawasaki)

Question 3

sytem for ensuring potency of vaccine from time of manufacture to time given it is given to a child

Answer 3

cold chain

Question 4

Principle of immunization

Answer 4

1. simultaneous administration of multiple vaccines is safe; 2. lapsed immunization does not require reinstitution of entire series; 3. in unknown immunization status; immunization should be initiated without delay on a schedule commensurate with the person’s current age

Question 5

fully immunized child

Answer 5

1dose BCG before reaching 12mos; 3DPT; 3Polio; 1measles; 3HepB; 3Hib; 3Rota

Question 6

when is 4th dose of HepB needed

Answer 6

1. 3rd dose given at age<2kg

Question 7

purpose of BCG protects against

Answer 7

EXTRAPULMONARY TB

Question 8

when is PPD recommended before giving BCG

Answer 8

1. suspected congenital TB; 2. hx of close contact to known/suspected infectious TB; 3. clinical findings and/or CXR suggestive of TB

Question 9

Immunization Sched: BCG

Answer 9

NB up to 12 mos: 0.5ml; >12mons: 0.1ml; INTRADERMAL; AR: abscess; ulcers at site; axillary LAD

Question 10

Immunization Sched: DPT

Answer 10

6;10;14wks; 0.5ml; IM; AR:fever; convulsions; irritability; prolonged crying

Question 11

Immunization Sched: OPV

Answer 11

8;12;16wks; 2-3drops; PO; AR: VAPP

Question 12

Immunization Sched: Hep B

Answer 12

after birth; 0-1-6mos; 0.5ml; IM; AR: pain at site; local redness; warmth; swelling

Question 13

Immunization Sched: Measles

Answer 13

9mos or 6mos in case of outbreaks; 0.5ml; SUBCUTANEOUS; AR: fever 5-12 days post vaccination; 1 week:rashes

Question 14

Immunization Sched: MMR

Answer 14

6mos after 1st measles; booster anytime bet 4-6yo; 0.5ml; SC; AR: pain; local redness; warmth and swelling

Question 15

Immunization Sched: Hib

Answer 15

2mo;4m;6mos; 1dose to unvaccinated ages 15-59; dose not earlier 6wks; booster at 12-15mos; last booster not earlier than 12yrs

Question 16

window time for varicella vaccine as postexposure prophylaxis

Answer 16

within 5 days

Question 17

Immunization Sched: PCV

Answer 17

2m;4m;6m; booster at 12-15m; IM; dose 1 can be given as early as 6wks; 1 dose to unvaccinated healthy children 24-59mos

Question 18

Immunization Sched: Rota

Answer 18

Rotarix(RV1): 2m;4m; Rotateq(RV2): 2m;4m;6m; as early as 6wks; final dose no later than 8mos;DO NOT BEGIN SERIES IN INFANTS >15wks 0days

Question 19

Immunization Sched: HPV

Answer 19

3-dose to girls age 11-12yrs(as early as 9yo) on 0; 1-2; 6m

Question 20

Immunization Sched: Rabies;pre-exposure

Answer 20

IM PVRV(Verorab): 0.5ml IM day 0;7;21; ID PCECV: 0.ml day 0;7;21

Question 21

Immunization Sched: Rabies;post-exposure to previously vaccinated

Answer 21

repeat vaccination at day 0;3 interval; no need to give Ig

Question 22

Passive Rabies Vaccine

Answer 22

ERIG:20u/kg or HRIG: 40u/kg I- 1/2 of the total dose infiltrated around the wound; 1/2 IM; only given to those who were bitten but has no previous vaccination