Epinephrine 1-1000

Question 1

Epinephrine 1:1000:class

Answer 1

sympathomimetic

Question 2

Epinephrine 1:1000:route

Answer 2

subcutaneousIVPB drip (rarely)

Question 3

Epinephrine 1:1000:adult dose

Answer 3

Asthmatic Bronchoconstriction:0.3 mg- 0.5 mg sqAllergic Reaction/Anaphylaxis:0.3 mg- 0.5 mg sqProfound Bradycardia:2-10 mcg/min IVPB continuous infusion, titrated to effect; mix 1 mg in 500 mL of NS or D5W

Question 4

Epinephrin 1:1000:pedi dose

Answer 4

asthmatic bronchoconstriction:0.01 mg/kg SQ; max of 0.3 mg per doseallergic reaction/anaphylaxis:0.01 mg/kg SQ; max of 0.3 mg per doseprofound bradycardia:0.1 - 1 mcg/kg/min IVPB continuous infusion, titrated to effect; mix 1 mg in 250 ml

Question 5

Epinephrin 1:1000:drug actions

Answer 5

alpha-peripheral vasoconstriction-increases BP in anaphylaxis-decreases vessel permeability-increases coronary and cerebral perfusionbeta 1-increases heart rate-increases contraction strengthbeta 2-bronchodilation

Question 6

Epinephrin 1:1000:indications

Answer 6

asthmatic bronchospasm refractory to Albuterol and Atrovent;allergic reaction/anaphylaxis;profound, symptomatic bradycardia refractory to other treatments

Question 7

Epinephrin 1:1000:precautions

Answer 7

monitor ECG closely;massage the site vigorously after SC injection;patients on beta blockers may need higher doses of epinephrine and/or Glucagon

Question 8

Epinephrin 1:1000:side effects

Answer 8

increases myocardial oxygen demand;tachycardia;HTN;myocardial ischemia/infarction;chest pain;arrhthmias;headache/flushing;nausea/vomiting;restlessness;tremors

Question 9

Epinephrin 1:1000:contraindications

Answer 9

asthma:heart disease/history of AMI;over 45;arrhythmias;laborallergic reaction:none