Dopamine Flashcards
Dopamine:class
sympathomimetic
Dopamine:route
IV piggyback
Dopamine:dose
bradycardia - 2-10 mcg/kg per mincardiogenic shock - 5-10 mcg/kg per minpost cardiac arrest hypotension - 5-10 mcg/kg per min
Dopamine:pedi dose
not used in pre-hospital setting
Dopamine:dilution
400 mg/250 mL D5W/NS800 mg/500 mL D5W/NSyield 1600 mcg/mL
Dopamine:drug actions
Low doses - dopaminergic effects; increases perfusion to kidneys and abdominal organs.Moderate doses - stimulate beta 1 receptors causing beta 1 adrenergic effects that increase the rate and force of ventricular contractions.High doses - alpha adrenergic effect producing peripheral arterial and venous constriction.
Dopamine:onset and duration
onset: 2-4 minutesduration: 10-15 minuteselimination: 24 hours
Dopamine:indications
hemodynamically significant hypotension in the absence of hypovolemia - hypotension, SBP 70-90, with S/S of cardiogenic shock; includes post cardiac arrest treatment of hypotension SBP<90Symptomatic bradycardia if atropine is ineffective(second line drug)
Dopamine:precautions
moniter BP and spO2patient on cardiac monitor12 leadIV access with large cathmonitor urinary outputflush after givingdont mix with sodium bicarbonateuse infusion pump if possiblecorrect hypovolemia first - don’t use vasopressors
Dopamine:interactions
inactivated in alkaline solutions(like bicarb)- may cause precipitation;beta blockers may blunt the inotropic response; phenytoin(Dilantin) - used for seizures - may cause hypotension, bradycardia, and seizures; MAO inhibitors - may potentiate effects
Dopamine:side effects
tachycardia- dose related; hypertension; increased myocardial oxygen demand- angina; headache; anxiety; nausea and vomiting; palpitations; ventricular arrhythmias- especially with high doses; tissue necrosis
Dopamine:contraindications
hypovolemic shock; tachydysrhythmias; ventricular fibrillation; patients with pheochromocytoma(adrenal gland tumor)