Amiodarone

Question 1

Amiodarone:class

Answer 1

antiarrhythmic

Question 2

Amiodarone:adult dose

Answer 2

cariac arrest:-first dose 300 mg IV/IO-second dose, if needed, 150 mg IV/IOstable wide QRS tachycardia:-first dose 150 mg over 10 min, repeat as needed if VT recurs-maintenance infusion of 1 mg/min for the first 6 hrs and 0.5 mg/min for next 18 hrs

Question 3

Amiodarone:pedi dose

Answer 3

refractory VF, pulseless VT:-5 mg/kg IV/IO, repeated to total dose of 15 mg/kg IV/IO per 24 hour, max single dose of 300 mgperfusing supraventricular and ventricular dysrhythmias:-5 mg/kg in 100 ml NS, slow IV over 30 min, repeated to total dose of 15 mg/kg IV per 24 hour, max single dose of 300 mg

Question 4

Amiodarone:drug actions

Answer 4

alters movement of sodium, potassium, and calcium through normal channels in all cardiac tissues;alpha and beta blocking properties;increase the refractory period of cardiac tissue;slows repolarization;decreases automaticity

Question 5

Amiodarone:indications

Answer 5

VF/VT cardiac arrest unresponsive to CPR, defibrilation, and vasopressor;recurrent, hemodynamically unstable VT;option in stable wide QRS tachycardia

Question 6

Amiodarone:side effects

Answer 6

rapid infusion may lead to hypotension;headache;heart block, bradycardia, CHF;liver and thyroid function abnormalities;dizziness;flushing;abnormal salivation

Question 7

Amiodarone:interactions

Answer 7

do not administer with other drugs that prolong QT interval, Procainamide;may potentiate bradycardia and hypotension with beta blockers and calcium channel blockers;may increase anticoagulant effects of Warfarin

Question 8

Amiodarone:contraindications

Answer 8

hypersensitivity to drug or iodine;in patients in cardiogenic shock, second or third degree AV block, bradycardia unless an artificial pacemaker is present;do not administer with other drugs that prolong the QT interval;trauma patients;use cautiously in patients with pulmonary, hepatic, or thyroid diseases