Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

PHAR 123 > Epilepsy > Flashcards

Epilepsy Flashcards

1
Q

What is the prevalence of epilepsy in Canada?

A

1% usually 18-44 years old and most enter remission

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the prevalence of epilepsy in Canada?

A

1% usually 18-44 years old and most enter remission

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the causes of epilepsy

A

genetic
tumour
infection
injury

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

T/F Most cases are cause by unknown means

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the tonic stage

A

stiffining of muscles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the clonic stage?

A

jerking movements

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is absence?

A

not consiousness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What does generalized mean

A

starts on both sides

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What does focal mean

A

on one hemisphere

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Seizures can be motor and non motor what does this mean

A

motor- twitch, repeated movements
nonmotor- change in emotion, sensation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What does frontal lobe do

A

motor and behavior

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What does occipital lobe do

A

vision

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what does temporal lobe do

A

hear and smell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what does parietal lobe do

A

sensation like touch

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What are the two general causes of seizures

A

excessive excite= inward Na and Ca- lots of glut and aspartate
low inhibition= inward Cl and out K- GABA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is surround inhibition

A

inhibition around a path so that its a more specific response

17
Q

What is the absolute refractory period

A

CANT send another signal during this period

18
Q

What is the relative refractive period

A

need a LARGER stimulus to send singal during this period

19
Q

What are the stages of a seizure

A

1-lose consciousness
2- muscle stiff and fall=tonic
3- muscle jerk=clonic
4 recover

20
Q

What are the Na channel blockers

A

Phenytoin, carbamazepine, lamotrigine, lacosamide

21
Q

What is the MOA of Na blockers

A

block channel OBVIOUSLY

22
Q

What are the two Ca channels and what is different?

A

T type= slow and are not active when awake= active during seizure= loss of conscious
High voltage= regulates glut and NorE

23
Q

What are the Ca channel blockers

A

gabapentin, pregabalin, ethosuximide

24
Q

What are the drugs that inhibit glutamate receptors (AMPA and NMDA)

A

lamotrigine, topiramate, levetiracetem(BLOCKS SV2A)

25
Q

WHat are the drugs that increase GABA

A

Benzos(pams)
barbiturates

26
Q

Why do antiepileptic drugs have Sio many side effects

A

Because they inhibit AMPA and NMDA which uses lots of different ion channels so any channel using them gets effected

27
Q

What are the general side effects of all antiseizure meds?

A

NDV
drowsy-sedate
ataxia-no coordination
confusion

PHAR 123 (18 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions