Blood Flashcards
What is the biggest part of blood?
plasma 55%=mostly water
cells= 45%
Where does hematopoiesis happen
red bone marrow= adult has it in sternum and hip
where does warfarin act
activation of factor IX, VII, X, II
1972 Canada vs soviet (Vit K factors)
Where does Apixaban’s act
Xa
Where does the intrinsic and extrinsic pathway connect
factor x activation
Where do heparins act
XA and IIA
Where do dabigatran’s act
activation of factor II
Which factor does LWMH act?
more for XA than IIA
How do antiplatelets work
COX inhibitor
stop aggregation or production
Grel’s, asprin
How do antiplatelets work
COX inhibitor
stop aggregation or production
Grel’s, asprin
What does thrombin do
generates fibrin to give structural integrity
factor IIA
How to get rid of clot
tPA activates plasminogen to lyse clot
What is the classification of anemia
<13g/dl for men
<1.5g/dl
Causes of anemia
bad production- cancer, low amount
destroying- because bad shape
bleed
Causes of anemia
bad production- cancer, low amount
destroying- because bad shape
bleed