enzymology (2) Flashcards
- shape of the key must fit into the lock
- active site is rigid
lock and key theory
active site is flexible
induced fit theory
what is the international unit
1 micromole of substrate/minute
what is the katal unit
1 mole of substrate/second
how many organs can be seen in high specificity
1-2 organs
how many organs can be seen in moderate specificity
3 - 4 organs
how many organs can be seen in low specificity
all organs
what are the high specificity
ACP, ALT, Amylase, Lipase
what are the moderate specificity
AST, CK, ALP
low specificity
LDH
what are the acute myocardial
creatinine kinase, aspartate aminotransferase, LDH
what are the hepatocellular disorders?
AST, ALT, LDS
what are the biliary tract obstruction?
ALP, GGT
what is the catalyze the removal or addition of electrons
Oxidoreductase
catalyze the transfer of functional group
Transferase
catalyze the hydrolysis or splitting of various bonds; work with the presence of water
hydrolase
catalyze the removal of groups from substrates without hydrolysis and contains double bonds
lyase
catalyze the intramolecular arrangement of the substrate compound
isomerase
catalyze the joining of 2 substrate molecules utilizing ATP
ligase