enzymology (2) Flashcards

1
Q
  • shape of the key must fit into the lock
  • active site is rigid
A

lock and key theory

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2
Q

active site is flexible

A

induced fit theory

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3
Q

what is the international unit

A

1 micromole of substrate/minute

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4
Q

what is the katal unit

A

1 mole of substrate/second

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5
Q

how many organs can be seen in high specificity

A

1-2 organs

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6
Q

how many organs can be seen in moderate specificity

A

3 - 4 organs

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7
Q

how many organs can be seen in low specificity

A

all organs

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8
Q

what are the high specificity

A

ACP, ALT, Amylase, Lipase

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9
Q

what are the moderate specificity

A

AST, CK, ALP

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10
Q

low specificity

A

LDH

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11
Q

what are the acute myocardial

A

creatinine kinase, aspartate aminotransferase, LDH

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12
Q

what are the hepatocellular disorders?

A

AST, ALT, LDS

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13
Q

what are the biliary tract obstruction?

A

ALP, GGT

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14
Q

what is the catalyze the removal or addition of electrons

A

Oxidoreductase

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15
Q

catalyze the transfer of functional group

A

Transferase

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16
Q

catalyze the hydrolysis or splitting of various bonds; work with the presence of water

A

hydrolase

17
Q

catalyze the removal of groups from substrates without hydrolysis and contains double bonds

A

lyase

18
Q

catalyze the intramolecular arrangement of the substrate compound

A

isomerase

19
Q

catalyze the joining of 2 substrate molecules utilizing ATP

A

ligase