Enzymes Flashcards

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1
Q

Some spontaneous chemical reactions occur at nearly imperceptibly _____ rates. ie. rusting

A

slow

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2
Q

The rate of many metabolically important chemical reactions is _________ to sustain life.

A

insufficient

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3
Q

What is activation Energy

A

A small amount of
energy that must be
invested and the energy required to break bonds

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4
Q

(EA) stands for…

A

activation energy

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5
Q

all reactions possess an _____ barrier that must be overcome for a reaction to occur

A

activation energy

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6
Q

energy is released when new bonds are….

A

formed

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7
Q

Enzymes are protein ….

A

catalysts

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8
Q

all enzymes are proteins, but not all proteins are…….

A

enzymes

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9
Q

What is a catalyst

A

A substance that speeds up the rate of a chemical reaction without being used up (consumed) in the reaction

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10
Q

after a reaction, the enzyme is able to catalyze……

A

another reaction

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11
Q

enzyme names end in

A

ase

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12
Q

Every chemical reaction involves both

A

making and breaking bonds

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13
Q

making bonds ________ energy

A

releases

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14
Q

breaking bonds ________ energy

A

absorbs

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15
Q

speed up the rate of a reaction by
lowering the………

A

activation energy

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16
Q

What remains the same in the chart

A

the net change in enthalpy

17
Q

Enzymes are proteins with…

A

specific 3-D shapes

18
Q

What is a substrate?

A

the reactant that an enzyme acts on when it catalyzes a chemical reaction

19
Q

Enzymes are defined by…

A

chemical bonds

20
Q

A substrate binds to a …..

A

particular site

21
Q

enzymes are _______ for the substrate to which they
bind

A

specific

22
Q

location to where the substrate binds to the enzyme is known as the……

A

active site (complimentary fit)

23
Q

What is Enzyme-Substrate Complex?

A

an enzyme with its substrate attached to the active site

24
Q

1st theory of active site

A

active site is rigid and exactly
complimentary to the substrate (lock and key)

25
Q

What is Induced-fit Model?

A

a model of enzyme activity that describes an enzyme as a dynamic protein molecule that changes shape to better accommodate the substrate

26
Q

Steps of enzymes and substrates

A
  1. Enzyme and substrate are available.
  2. Substrate enters the active site and forms weak bonds
    while the enzyme’s conformation changes to
    accommodate the substrate.
  3. Bond(s) are either broken or formed within the
    substrate.
  4. Altering the bonds within the substrate alters the
    conformation of the protein slightly; loses affinity for
    product and releases the molecules.
27
Q

Induced fit is basically..

A

when enzymes conformation changes to better accommodate the substrate

28
Q

Rates of chemical reactions are dependent on the what factors?

A

temperature

pH

concentration of substrate

concentration of enzyme

Inhibitors

Cofactors/Coenzymes

29
Q

Which chemical reaction are denaturation?

A

temperature and pH

30
Q

An enzyme’s three-dimensional shape is defined by various….

A

chemical bonds

31
Q

The rate at which an enzyme converts substrate into product can be increased by ___________________.

A

increasing, substrate concentration

there is a limit !

32
Q

Enzyme is saturated when….

A

when some substrate concentration all of the enzymes active sites are bound to substrate.

33
Q

Adding more _______ will not increase the rate. But, Adding more _____ will increase the rate.

A

substrate, enzyme

34
Q

Cofactors may be…

A

inorganic or organic

35
Q

What is cofactor ?

A

nonprotein components needed for
enzymes to function

36
Q

What is coenzymes

A

organic nonprotein cofactors needed for
some enzymes to function

37
Q

Inorganic cofactors are typically…

A

metal ions

38
Q

Organic cofactors (“coenzymes”) are typically…

A

vitamins or are derived from vitamins.

39
Q
A