Environmental and Nutrition Flashcards
What is the single largest preventable cause of death?
smoking
True or False? After 15 years of abstinence, mortality rate of ex-smokers approaches those who have never smoked.
True
Smoking is a major risk factor for what three things?
- myocardial infarction
- increased BP
- increased blood cholesterol
True or False? Smoking initiates MI’s and increases risk of 2nd heart attack.
True
___ contributes to erosion and instability of atherosclerotic plaques.
Smoking
True or False? Atherosclerosis of coronary arteries and aorta more sever in smokers.
True
What is the mechanism by which atherosclerosis of coronary arteries and aorta in smokers?
Nicotine and carbon monoxide:
- decrease in plasma high density lipoproteins levels
- increase in plasma fibrinogen
- increase in leukocyte counts (predisposes to MI’s and stroke)
What is the single most common cancer death in both men and women?
lung cancer
What percentage of lung cancer deaths are caused by smoking?
85%
Cigarette smokes contains thousands of what three things?
- carcinogens
- tumor promoters
- cilio-toxic agents
What are the 6 cancers attributed to smoking?
- larynx
- esophagus
- bladder
- adenocacinoma
- pancreas
- uterine/cervix
What other diseases are smokers at higher risk for?
- chronic bronchitis/emphysema
- peptic ulcer disease
- ocular disease
- for women:
- osteoporosis
- thyroid disease
- earlier menopause
True or False? 20-40% low birth weight attributable to maternal cigarette smoking.
True
People with ______ may later in life have increased susceptibility to respiratory infections, otitis media, and lasting long term damages to physical, cognitive, and emotional development.
fetal tobacco syndrome
Environment tobacco smoke is a risk factor for what 4 diseases?
- lung cancer
- respiratory illness and hospitalizations
- coronary artery disease
- sudden cardiac death
Explain ethanol metabolism.
Ethanol is converted into acetaldehyde in the microsomes or peroxisomes. Acetaldehyde which is toxic, is quickly converted into acetic acid in the mitochondria and goes into the Kreb’s cycle.