Environment/Rhabdo

Question 1

what is the cutoff CK value for diagnosing exertional rhabdo?

Answer 1

> 5x ULN

Question 2

t/f you need appropriate clinical history and lab findings together to diagnose exertional rhabdo

Answer 2

true

Question 3

what are the three labs you trend during the treatment for exertional rhabdo?

Answer 3

CK, CMP, UA

Question 4

what is the target UOP in ml/hr for treatment of exertional rhabdo in inpatient treatment?

Answer 4

200-300ml/hr

Question 5

what hematologic condition increases the risk for death in rhabdo?

Answer 5

sickle cell trait

Question 6

what is McArdle’s disorder?

Answer 6

myophosphorylase deficiency

Question 7

in general if you see a case of exertional rhabdo after low to moderate exertion, what type of conditions should you be worried about?

Answer 7

metabolic myopathy - myophosphorylase deficiency or CPT deficiency

Question 8

what is the general pathophysiology that is occurring in exertional rhabdomyolysis on a cellular level in the muscle?

Answer 8

myonecrosis

Question 9

t/f diagnosis of exertional rhabo requires severe muscle symptoms and lab evidence of myonecrosis

Answer 9

true