Enfermedades hepáticas Flashcards

1
Q

Tumores hepáticos benignos

A
  • Adenoma hepatocelular
  • Hiperplasia nodular focal
  • Hemangioma
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2
Q

Adenoa hepatocelular

A
  • Hepatocelular
  • Hepatocitos sin atípicas proliferan (>5cm riego maligno)
  • Mujer edad fértil + consumo AO
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3
Q

Dx adenoma hepatocelular

A

Captación precoz homogénea y completa de contraste sin cicatriz central

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4
Q

Tx adenoma hepatocelular

A

Suspender AO
Cx varones si tienen gran tamaño

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5
Q

Hiperplasia nodular focal

A
  • Hepatocelular
  • Proliferación de hepatocitos normales por malformación AV preexistente
  • Mujer jóven
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6
Q

Dx hiperplasia nodular focal

A

Captación centrifuga de contrastes. Cicatriz estrellada central
Tx: conservador

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7
Q

Hemangioma

A
  • Mesenquimal
  • Tumor vascular
  • Mujer 30-50
  • rara vez maligno
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8
Q

Dx hemangioma

A

Relleno centrípeto lento
Tx: conservador, qx si es grande

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9
Q

Tumor maligno más frecuente en varones

A

Carcinoma hepatocelular

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10
Q

Causas Carcinoma hepatocelular

A

1) Cirrosis
2) Inf. crónica VHB
3) Inf. crónica VHC
4) Otros

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11
Q

Clínica Carcinoma hepatocelular

A
  • Asintomatico
  • Dolor/masa abdominal
  • Fenómenos paraneoplásicos (eritrcitosis, hipercalcemia, porfiria hepatocelular o crioglobulinemia)
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12
Q

Detección precoz Carcinoma hepatocelular

A

Prueba dx elección: Cribado CHC → Ecografía semestral
*Nódulo hipoecogénico

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13
Q

Una vez detectado el nódulo (>1cm) se confirma dx

A

Rx (no invasivo)
- Patron vascular visible por contraste
- Lavado de contraste (washout) fase portal y tardía

Citohistología (invasiva)

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14
Q

Elección de tx para Carcinoma hepatocelular

A

Clasificación BCLC (Barcelona Clinic LiverCancer)
- Extension tumoral
- Funcionalistas hepática
- Estado px

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15
Q

Tx de hepatocarcinoma avanzado (BCLC C):

A

1° linea: Sorafenib, Lenvanitib, Atezolizumab/Bevacizumab

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