Energy and Metabolism 2 Flashcards

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1
Q

How to enzymes lower the activation energy?

A
  1. Orient substrates correctly- linkages needed to be made are brought closer
  2. Facilitates bond breaking to reach transition state
  3. Provides favorable microenvironment
  4. Changes bond arrangements to make easier attachment
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2
Q

Enzyme functions are affected by the environmental factors such as

A

pH and temperature

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3
Q

no homeostasis= no functioning enzymes= no _____

A

metabolism

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4
Q

competitive inhibitors

A

inhibitor binds to the active site of enzyme, no allowing the lock and key fit to occur

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5
Q

noncompetitive inhibitors

A

binds to another part of the enzyme to change the overall shape. Enzyme no longer fits into the substrate

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6
Q

Give examples of enzyme inhibitors

A

poison, toxins, antibiotics

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7
Q

If metabolic pathways are not controlled..

A

chaos occurs

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8
Q

The main way how cells regulate metabolic pathways are

A

regulation of genes

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9
Q

regulation of genes-

A

express more or less of a certain (protein) for example to increase or decrease the presence

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10
Q

allosteric regulation

A

inhibits or stimulates enzyme’s activity

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11
Q

allosteric regulators are made up of

A

polypeptide subunits

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12
Q

Name the two types of allosteric regulators

A
  1. Allosteric Activator

2. Allosteric Inhibitor

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13
Q

Allosteric Activator

A

presence of activator exposes the different active sites in a STABLE form

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14
Q

Allosteric inhibitors

A

presence of inhibitor causes all active sites to be covered in a STABLE form

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15
Q

Allosteric Cooperativity

A

substrate addition activates other three active sites

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16
Q

Feedback Inhibition definition

A

end product shuts down the metabolic pathway

17
Q

What is the main benefit to feedback inhibition?

A

To save energy, no energy is wasted in making repeated products, and that energy can be used somewhere else useful in the cell

18
Q

Compartmentalization within the Eukaryotic cells allows:

A

isolation, isolation of enzymes to stop their function

19
Q

example of compartmentalization

A

lysosomes, not fed= not digestive

20
Q

how mitochondria can control enzymes

A

contains a chemical gradient structure where different enzymes can be isolated within

21
Q

The three main types of work that the cell can do

A

chemical, transport, and mechanical

22
Q

to do work within the cell, ____ is needed.

A

energy

23
Q

ATP is the cells _____.

A

battery

24
Q

ATP is composed of

A

a ribose (sugar), adenine, and three phosphate groups

25
Q

ATP is used efficiently to

A

diffuse concentrations of different molecules from high concentration to lower concentration

26
Q

energy is released when

A

phosphate bonds in ATP are broken

27
Q

breaking of the phosphate bonds results in

A

change to lower free energy

28
Q

by changing the free energy…

A

more energy is provided and increases the free energy to do other things within the cell

29
Q

Use _____ to break up ATP.

A

hydrolysis

30
Q

ADP can become ATP by using ____.

A

the energy from the catabolic respiration reactions

31
Q

the conversion between putting energy into ATP to make ADP and release energy is

A

continuous and keeps regenerating