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Reproductive - Y3* > Endometrial Cancer > Flashcards

Endometrial Cancer Flashcards

1
Q

How do you find out histological type, grade and lymphovascular space invasion?

A

Through microscopy

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2
Q

How do you find out stage?

A

Through surgery or MRI

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3
Q

What is Type 1 endometrial cancer? Epidemiology and cause?

A

Endometriod carcinoma

It’s the commonest, caused by unopposed estrogen.

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4
Q

What is the precursor for Type 1 endometrial cancer?

A

Hyperplasia with atypia

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5
Q

What is Type 2 endometrial cancer? Epidemiology and prognosis?

A

Uterine serous and clear cell carcinoma

Typically more for older women, high grade, more aggressive, worse prognosis.

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6
Q

What is the precursor for Type 2 endometrial cancer?

A

Serous intraepithelial carcinoma

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7
Q

What are the stages for endometrial cancer?

A

1A, 1B
2
3A, 3B
4

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8
Q

What is stage 1A?

A

Inner half thickness of the myometrium

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9
Q

What is stage 1B?

A

Outer half thickness of the myometrium

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10
Q

What is stage 2?

A

Invasion of cervix

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11
Q

What is stage 3A?

A

Invasion of serosa/adnexes

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12
Q

What is stage 3B?

A

Pelvic or para-aortic nodes (forgot about these when trying to memorise)

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13
Q

What is stage 4?

A

Distant metastases, spread to the peritoneal organs/lymph nodes

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14
Q

What is the treatment for early stage disease?

A

Surgical and washings

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15
Q

What is the treatment for high risk histology?

A

Chemotherapy

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16
Q

What is the treatment for advanced stage disease?

A

Radiotherapy

17
Q

What is the treatment for palliation?

A

Progesterone

18
Q

What are the investigations for endometrial cancer?

A

Bloods
Ultrasound - TV/TA
Biopsy

19
Q

56 y/o woman comes in with PV bleeding. She has been menopausal for 5 years. TVUS shows endometrial hyperplasia, and further staging via MRI shows that the cancer has spread to the para-aortic lymph nodes. What stage of endometrial cancer is this?

A

Stage 3B

Reproductive - Y3* (30 decks)

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