Complications in Pregnancy 2 Flashcards
What are the different stages of chronic hypertension in pregnancy?
- Mild – 140-9/90-9
- Moderate – 150-9/100-9
- Severe – 160/>110
What antihypertensive drug should be stopped for pregnancy?
ACEi
What is the potential complication of maternal HTN?
Placental abruption
What is it called when a woman has new onset HTN when pregnant?
Gestational HTN
What is pre-eclampsia?
New onset HTN
Proteinuria (300mgms/24 hours)
This is very important.
What are the potential pathophysiology processes of pre-eclampsia?
- Secondary invasion of maternal spiral arterioles by trophoblasts –> decreased placental perfusion
- Imbalance between vasodilators/vasoconstrictors in pregnancy
What are the risk factors for pre-eclampsia?
- Immunological
- FH
- 1st pregnancy
- High BMI
- Underlying medical conditions, e.g. SLE
What are the maternal complications of pre-eclampsia?
- Eclampsia (seizures)
- Severe HTN
- HELLP
- DIC
- Renal failure
- Pulmonary oedema
- CVS failure
What is HELLP syndrome?
Haemolysis
Elevated Liver enzymes
Low Platelet
Most common in women with pre-eclampsia or eclampsia.
How does HELLP present?
Wide range of non-specific symptoms
Fatigue, malaise Fluid retention Excess weight gain Pain in the upper right or middle of the abdomen Nausea and vomiting Headache, Blurry vision
What is DIC?
Disseminated intravascular coagulation.
A condition in which blood clots form throughout the body, blocking small blood vessels. .
What are the foetal complications of pre-eclampsia?
- Impaired placental perfusion
- Intrauterine growth restriction (IUGR)
- Prematurity
- PN mortality
What is the management for pre-eclampsia?
Only ‘cure’ is delivery of baby and placenta.
- BP check
- Symptomatology
- CTG
- Aim for foetal maturity
- Risks may persist into puerperium (postpartum period)
How do you treat eclampsia seizures?
- Magnesium sulphate bolus + IV infusion
- Control of BP
- Avoid fluid overload
What is the risk of maternal diabetes?
Increased risk of pre-term delivery
Worsening of maternal nephropathy