Endocrine System/ Cara Gambina Flashcards
Pancreas (Alpha cells)
Causes liver to release glycogen
Thyroid/(Calcitonin)
Responsible for increasing the deposition of calcium into bone
Pituitary gland/(Prolactin)
Causes the production of milk in woman
adrenal glands/Aldosterone
Causes the distal convoluted tubule of the nephron to retain more sodium at the loss of a 2 thirds less potassium.
Thyroid hormone
Responsible for driving your metabolism and raising your metabolic rate.
Insulin
Causes glucose and amino acids to be taken up by the muscle and adipose tissue and it also causes anabolic reactions in cells.
Oxytocin
associated with bonding in humans.nursing/ childbirth
Hypothalamus
Detects a significant deviation from set set point, it produces hormones called tropic hormones.
These tropic hormones go to the pituitary gland, which is located inferior to the hypothalamus in the sphenoid bone, via a very small portal vain and signal the anterior pituitary gland to start making 1 or two more hormones.
Infundibulum
Connecting the hypothalamus and the pituitary gland.
Infundibulum contains axons that go to centers of the hypothalamus to the posterior pituitary gland,
Diencephalon
Sits in the center of the brain
Thalamus
Hypothalamus
Thalamus
Manly a relay point for afferent(sensory) nerve signals in the brain.
Hypothalamus
Monitors those signals closely
Produces hormones if sense a deviation.
Pineal gland
Is also part of the Diencephalon. The pineal gland receives sensory information from the eyes and helps establish circadian rhythms( day night cycles). It does so via the hormone melatonin which is produced at night.
Thyroid gland
Neck below the larynx and it wraps around the anterior trachea.
The thyroid gland produces an iodine containing hormone called thyroid hormone or thyroxine.
This hormone is vital for the driving your metabolism and raising your metabolic rate.
Parathyroid glands
4 pea sized - behind the thyroid
Maintaining a minimum blood calcium levels via the production of parathyroid hormone.
This hormone increases uptake of calcium in the kidneys and intestine as well as increases the activity of osteoclasts which break down bone releasing calcium in the process.
Adrenal glands and the pancreas
Located deep within the abdominal cavity.
Pancreas
Releases insulin
Glucagon
Is produced in response to low blood sugar.
Causes the liver to release glycogen stores into the body and produce new glucose from amino acids.
Pars nervosa
The axons they decend from the hypothalamus terminate in the pars nervosa.
Adrenal glands
Rest in the superior surface of the kidneys and they are in reality 2 glands. In the center of the adreanal gland is called the adrenal medulla and composed of nervous tissue.
Axons from the sympathetic nervous system stimulate chromafin cells to produce adrenalin ( epinephrine) and noradrenalin( nor epinephrine)
Calcitonin
Is a hormone that increases the activity of osteoblasts in your bone.
Parathyroid hormone
Does this by increasing the activity of bone eating osteoclasts as well as increasing the absorption of calcium in the intestines and rea sorbitol in the kidneys.
Thyroid
Calcitonin ( increasing calcium)
Thyroxine ( metabolism)
Pineal gland
Melatonin
Adrenal glands
Located posterior and inferior to the stomach and is responsible for producing 2 hormones that help regulate blood sugar.
Anterior pituitary gland
Acidophils
Acidophil
Pancreas
Acini cells
Pancreatic juice which aids digestion
Pancreatic islet cells
Produce the endocrine hormones of the pancreas.
Endocrine organs
Secretory epithelia that release hormones
STEROID HORMONES
Interns into cell change mRNA expression
NONSTEROID HORMONES
Trigger the activation of second messengers
Second messengers
Trigger changes inside cells
Tropic hormones
Hormones that cause release of other hormones.
Hypothalamus (tropic hormone)
Secretes hormones that stimulate anterior pituitary gland.
Anterior pituitary gland
Makes (ACTH) adrenocorticotropic hormone
HUMORAL stimuli
Response to rising/ falling levels ( non- hormone) substances in blood.
Neural stimulus
Trigger hormone release “ fight or flight” or nipple stimulation.
Posterior pituitary
Does not make hormones.
Anterior pituitary hormones
Are Peptides or proteins - second messengers
Anterior pituitary gland ( regulated)
By other tropic hormones and negative feed back.
Anterior pituitary hormones
Stimulate growth/ release of additional hormones.
GHRH
Growth hormone release hormone. Regulated by hypothalamus - pituitary gland
Prolactin
Triggers milk production in woman
FSH and LH
Trigger sperm/ egg development, release, sex hormone production.
(ACTH) Adrenocorticotropic hormone
Anterior pituitary triggers release from ( outer) of the adrenal gland.
Glucocorticoids ( cortisone and cortisol)
Reduce inflammation, raise blood sugar.
Monetalocorticoids
Signal kidney to retain water and sodium.
Tenon signal
Kidneys sense when your blood drops send hormonal signal
Thyroid- stimulating hormone (TSH)
Made in anterior pituitary.
Thyroid hormones
Act on most of your cells to regulate growth, calcium levels, body temp.
The thyroid
(t4) (t3) increase rate of glucose burning, raises body temperature
The thyroid
Tissues bt. follicles make calcitonin,which triggers calcium storage in bones.
Hyperthyroidism
Autoimmune damage and cancer
Hypothyroidism
Occur if immune system destroys thyroid tissue
Parathyroid glands
Attached to thyroid/ hormone(PTH) keeps blood calcium up
parathyroid gland(PTH)
Increases calcium absorption/ prevents kidneys from getting rid of hormone: triggers bone break down.
Overactive parathyroid
Can lead to osteoporosis
Pancreatic hormones
Regulate blood sugar and growth
TSH- thyroid- stimulating hormone
Made in anterior pituitary gland
Increased growth and hormone release from thyroid gland in the neck.
Thyroid hormones act on most of your cells to regulate growth, energy use and body temperature, calcium levels and sexual development
Thyroid hormone - follicles
(t4) and ( T3)
Increase the rate of glucose burning raised body temperature
Tissues in follicle of Thyroid
Makes calcitonin, which triggers calcium storage in bones.
Hormonal stimuli
Ex, hypothalamic hormones stimulate the anterior pituitary gland to secrete it’s hormones
Hormonal
Hypo->pituitary gland->
Humoral stimulus
Capillary blood contains low concentration of ca2 which stimulates
Neural stimulus
Sympathetic fiber stimulates adrenal medulla cells
Norepinephrine and epinephrine during periods of stress.
Endocrine organs
Pituitary gland, thyroid, parathyroid, adrenal, and pineal glands, and thymus, pancreas and the gonads.
ADH hypo secretion
Diabetes insipidus
Diabetes insipidus
Excessive urine output
Goiters
Deficient in iodine
Cretinism
Dwarfism
Myrdema
Physical and mental sluggishness
Hypothyroidism
Calcitonin
Decreases blood calcium levels by causing calcium to be deposited into bones.
Thyroxine
Majors hormone secreted by thyroid follicles
Renin
An enzyme produced by kidneys when blood pressure drops.
Type 2 diabetes
Produce insulin, but for some reason their insulin receptors are unable to respond to it.
Antidiuretic hormone ( ADH)
Peptide
Retention of water by kidneys
Hypothalamus
Oxytocin
Peptide
Contracts uterus bonding
Nervous system
( hypothalamus)
AL-pituitary gland
(GH) growth hormone
Protein
Stimulates growth
Hypothalamic
(FSH) follicle-stimulating hormone
Protein
Stimulate ova and sperm
Hypothalamic hormones
(TSH) thyroid- stimulating hormone
Protein
Stimulates thyroid gland
Thyroxine in blood
Hypothalamic hormones
Adrenocortrpic hormone (ACTH)
Protein
Stimulates adrenal correct to secrete glucocorticoids
Parathyroid
PTH
Peptide
Raises blood calcium level
Adrenal medulla
Epinephrine and norepinephrine
Nervous system
Raise in blood glucose level
Adrenal cortex
Glucocticoids
Steroids
Increase blood glucose
ACTH
Adrenal cortex
Monetalocorticoids
Steroids
Promote transient ion of Na and excretion of K in kidneys
Pancreas
Insulin
Protein
Glucagon
Protein
Aldosterone
Steroid hormone
Adrenal cortex
Regulation of blood pressure.
Cortisol
Released in response to stress hormone steroid
Low blood glucose
From adrenal cortex