endocrine system Flashcards
a system of glands and cells that secrete hormones to regulate and integrate body systems
endocrine system
organs that secrete substances into the blood in response to stimuli
endocrine glands
chemical messengers, released into the interstitial fluid which then enters the bloodstream. released in one part of the body to regulate activity in another
hormones
hormones bind to these on the cell membranes of target cells/organs. changes the shape when bound.
hormone receptors
increase in target cell receptors due to a lack of circulating hormone, increases sensitivity to the hormone
upregulation
decrease in target cell receptors due to an excess of circulating hormone, decreases sensitivity to the hormone
down regulation
will hormone levels fluctuate depending on demand and normal body rhythms?
yes
what can alter normal hormone levels?
environment, stress, inflammation, pathologies
what system governs secretion control (chemical changes in blood)
nervous system
in most cases, hormone levels are managed through what feedback loops?
negative
2 endocrine glands that regulate all aspects of growth, development, metabolism, homeostasis
hypothalamus, pituitary
major integrating centre between the nervous and endocrine systems. receives input/information from many different structures. hormonally, regulates the synthesis and release of anterior pituitary hormones. neurologically, regulates the synthesis and release of posterior pituitary hormones
hypothalamus
small endocrine gland that sits in the sella turcia of the sphenoid bone. has anterior and posterior lobes
pituitary
pituitary lobe. release/inhibition of its hormones is controlled hormonally by the hypothalamus
anterior pituitary
hormone that stimulates tissue growth, promotes healing and tissue repair, increases the use of lipids for energy, decreases cellular uptake of glucose/elevates blood glucose levels. released in bursts every few hours
human growth hormone (hGH)
hormone that stimulates the release of thyroid hormones by the thyroid gland. its release is dependent on the level of thyroid hormones in the blood
thyroid stimulating hormone (TSH)
hormone that stimulates the release of cortisol from the adrenal glands. release increases with stress-related stimuli, macrophage activity
adrenocorticotropic hormone (ACTH)
hormone that triggers ovulation, release of testosterone from testes
lutenizing hormone (LH)
hormone that triggers ovarian follicle development, sperm production in testes
follicle stimulating hormone (FSH)
initiates and maintains milk production in the mammary glands
prolactin (PRL)
hormone that stimulates melanocytes
melanocyte stimulating hormone (MSH)
lobe of pituitary gland. release/inhibition of its hormones is controlled neurologically by the hypothalamus
posterior pituitary
hormone. during delivery it inhances smooth muscle contraction of the uterus, post partum it stimulates milk ejection
oxytocin