endocrine disorders Flashcards
which part of the body is the main control center for hormonal regulation?
hypothalamus
(what is the mechanism) the control of hormone release in response to changes in the extracellular fluid levels or iron levels
humoral stimuli
(what is the mechanism) the release of hormones in response to hormones released by other endocrine glands
hormonal stimuli
(what is the mechanism) the release of hormones in response to neural stimulation
neural stimuli
describe negative feedback loop in hormone regulation
a reaction that causes a decrease in function to help maintain homeostasis
what is metabolism
cellular process taht occurs with the cells of the body to produce energy and facilitate cellular growth and repair, for the purpose of maintaining homeostasis
hormone levels are primarily controlled though ______ feedback loops, in which ______ levels of hormone inhibit its further release
negative, rising
example of positive feedback loop
oxytocin is released from the posterior pituitary gland, which stimulates muscle contractions taht push the baby through the birth canal
example of negative feedback loop
negative feedback loop occurs when a change in one directions causes a difference in the opposite direction. When thyroid-releasing hormone (TRH), which signals the anterior pituitary gland to release thyroid-stimulating hormone (TSH), causing the thyroid to release hormones. As newly released thyroid hormone levels increase the hypothalamus stops producing TRH, causing the anterior pituitary gland to stop producing TSH
endocrine problems are usually cause by
hormone imbalances
addison’s disease
the adrenal gland does not produce enough cortisol (stress hormone) and aldosterone. Causes low sodium and glucose and high potassium, dehydration, and weight loss
Acromegaly
Cause: excessive growth
Rationale: in most cases it is caused by a benign tumor in the pituitary gland
-GHRH, GH, IGF-1
cushing’s syndrome
causes: excess cortisol and increased secretion of adrenocorticotropic hormone (HCTH)
rationale: caused by excess of glucocorticoids. The excess may be due to long term use of steroids, a pituitary tumor, or adrenal adenoma
diabetes mellitus
Cause: lack of insulin or insufficient use of insulin
Rationale: DM develops when the pancreas does not make enough insulin or insulin is not working the way it should
hypoparathyroidism
Cause: low levels of parathyroid hormone (PTH)
rationale: hypoparathyroidism may be caused by a congenital anomaly, decreased activity of one or more of the four parathyroid glands, radiation near the glands (in the neck), surgery near the glands, or autoimmune disease