Endocrine Disorders Flashcards
Deficiency of antidiuretic hormone due to a disorder of the posterior pituitary gland resulting in the inability for the kidneys to conserve water
Diabetes insipidus
Causes of diabetes insipidus (7)
- Head trauma
- Tumors
- Surgery
- Radiation
- CNS infections
- Malignant tumors
- Failure of renal tubules
Urine chemistry manifestations of diabetes insipidus (2)
- Decreased urine specific gravity
- Decreased urine osmolality
Serum chemistry manifestations for diabetes insipidus (2)
- Hypernatremia
- Increased serum osmolality
Other manifestations of diabetes insipidus (7)
- Polyuria
- Polydipsia
- Dehydration
- Weight loss
- Muscle weakness
- Dry skin
- Hemoconcentration
Excessive release of ADH causing the inability to excrete an appropriate amount of urine and developing fluid retention and dilutional hyponatremia
Syndrome of inappropriate secretion of antidiuretic hormone (SIADH)
Causes of SIADH (6)
- Neoplastic tumors
- Head injury
- Meningitis
- Respiratory disorders
- Some medications
- Nicotine
Urine chemistry manifestations of SIADH
Increased urine specific gravity and osmolality
Serum chemistry manifestations of SIADH (2)
- Hyponatremia
- Decreased serum osmolality
Other manifestations of SIADH (9)
- Mental confusion
- Irritability
- Lethargy
- Seizures
- Weakness
- Anorexia
- N/V
- Increased ADH levels
- Weight gain
Hypothyroidism manifestations (11)
- Fatigue/weakness
- Increased sensitivity to cold
- Constipation
- Dry skin, brittle hair/nails
- Weight gain
- Deepened, hoarse voice
- Joint pain
- Hyperlipidemia
- Anemia
- Depression
- Menstrual disturbances
Hyperthyroidism manifestations (12)
- Anxiety
- Irritability
- Insomnia
- Fatigue
- Tachycardia
- Tremors
- Diaphoresis
- Intolerance of heat
- Weight loss
- Exophthalmos
- Diarrhea
- Light/absent menstrual cycle
