Empiric Therapies

Question 1

What is the empiric therapy of fever of unknown origin when the CSF status is known or unknown?

Answer 1

Known normal CSF: IV flucloxacillin and gent

If unknown CSF: IV Flucloxacillin and ceftaxime

Question 2

Empiric therapy for UTI

Answer 2

Not sick: oral trimethoprim or co-trimoxazole

Sick: IV benzylpenicillin and gent

Question 3

Pneumonia

Answer 3

Mild: oral amoxicillin or roxithromycin if considering mycoplasma

Moderate: IV benzylpenicillin or PO roxithromycin if considering mycoplasma

Severe: Flucloxacillin iv and Gent iv and Azithromycin iv If considering Mycoplasma

Question 4

Meningitis

Answer 4

Ceftriaxone IV

If less than 2 months use cefotaxime and benzylipenicillin

Question 5

Encephalitis

Answer 5

Aciclovir

Question 6

Ottitis media

Answer 6

Consider no antibiotics for 48 hrs (especially if >2y old) or
Amoxycillin 15 mg/kg (500 mg) po 8H

Question 7

Osteomyelitis

Answer 7

Flucloxacillin

And cefotaxime if less than 5 or non-Hib immunised