Embryology/Development Flashcards
1
Q
Timeframe for zygote to get into uterus and implant?
A
- 5 days to get into uterus and begin impantation
- 11 days to fully inplant into endometrium
2
Q
Zygote (2)
A
- Egg that’s been fetrilized
- Fertilization occurs in uterine tube’s ampulla
3
Q
Morula (3)
A
- Blastomeres at 16 cell stage
- Inner cell mass (embryoblast) that forms embryo and components of fetal membranes
- Outter cell mass (trophoblast) contribute to fetal membranes and placenta
4
Q
Zona Pellucida Functions (5)
A
- Barrier that prevents multiple fertilizations
- Filter to allow uterine secretions to reach embryo
- Immunological barrier between mother and embyro
- Prevents blastomeres from dissociating
- Prevents premature implantation (before embryo reaches uterine wall)
5
Q
Lacuna (2)
A
- Blood filled spaces in embryotic pole of syncytiotrophoblast
- Form primative uteroplacenta circulation
6
Q
Connecting Stalk (3)
A
- Portion of extraembryonic mesoderm that connects embryo to chorion (becomes fetal portion of placenta)
- Fills space left over from chorionic cavity formation
- Eventaully become umbilical
7
Q
Buccopharyngeal and Cloacal Membranes
A
- Buccopharyngeal becomes mouth
- Cloacal becomes anus
- 2 layers so they’ll rupture
8
Q
Gastrulation (3)
A
- Bilayer becomes 3 germ layers (enod, meso, & ectoderm) once epiblast cells invaginate in the midline
- Primitive streak and primitive pit/primitive node form
- Week 3
9
Q
Endoderm Cells
A
- Develop into: lining of digestive, respiratory, urogenital systems, and pharyngeal pouches of head and neck region
10
Q
Mesoderm Cells
A
- Develops into: skeletal, smooth, & cardiac muscle, most cartilage & bone, dermis of skin, and portion of kidneys & gonads
11
Q
Ectoderm Cells
A
- Develop into: nervous system and epidermis of skin
12
Q
Notochord (3)
A
- Specialized rod of mesoderm cells that migrated rostrally from primitive node/pit
- Forms basis of vertebral column and ends up in nucleus pulposis of discs
- Signals formation of: neural plate, groove, & fold, CNS from endoderm
13
Q
2 vs 3 layered membranes
A
- 2 layered membranes rupture
- 3 layered membranes don’t rupture
14
Q
Cells Migrating from Primitive Streak
A
- Rostral cells of primitive streak form more midline structures (axial muscles & skeleton, and notochord
- Caudal cells form more lateral structures
15
Q
Prechordal Plate
A
- “Head organizer” that forms parts of head and brain
16
Q
Neurulation (3)
A
- Formation of primitive nervous system
- Facilitated by notochord secreting inducing factors
- Ectoderm proliferates and thickens into neural plate
17
Q
Neural Crest Cells Derivatives (9)
A
Derive into:
- spinal, autonomic, and cranial nerve ganglia
- Schwann cells
- Medulla of adrenal gland
- Meninges
- Pigment cells of skin
- Glial cells
- C cells of thyroid
- Conotruncal regions of heart
- Connective tissue, some bones, and dermis of back & head
18
Q
Anterior & Posterior Neuropores
A
- Anterior closes day 25 and causes Exencephaly if done incorrectly
- Posterior closes day 27 and causes Spina Bifidia (on a spectrum) if done incorrectly
19
Q
Paraxial Mesoderm (3)
A
- Most axial
- Form longitudinal columns on each side of notochord/neural tube
- Differentiate into 44 pairs of somites