Embryology Flashcards
which part of mesoderm does urogenital system arise from?
intermediate mesoderm
which end does the primitive streak form at?
caudal
what does the primitive streak do?
sets up the body axis (so embryo knows which way is up)
mesoderm splits into 3:
paraxial (midline)
intermediate
lateral plate
coelomic epithelium will eventually develop into?
peritoneum, pleura and the surface of the ovary
the development of the genital ducts:
- mesonephric duct
- paramesonephric duct
which is associated with male and which is associated with female?
mesonephric - male
paramesonephric - female
but embryo has both
germ cells differentiate into _____ then into _______ _______
oogonia
primary oocytes
somatic support cells differentiate into _________ cells and surround the primary oocytes
granulosa/follicular
theca cells
endocrine related cells and they’re very important for oestrogen development (they produce the substrate)
paramesonephric duct 3 parts:
- cranial portion
- horizontal portion
- caudal portion
what area connects the mesonephric tubules to the testis cords
rete testis
in male development, what do somatic support cells develop into?
Sertoli cells
sertoli cells roles
- secrete AMH to breakdown paramesonephric duct
- stimulate gonadal ridge cells to form leydig cells
what do leydig cells secrete?
testosterone
Persistent Mullerian (paramesonephric) Duct Syndrome
paramesonephric ducts fail to regress
Present with:
Uterus, vagina and uterine tubes
Testes in ovarian location
Male external genitalia
