EM Block II Flashcards
Describe visceral pain
Obstruction, ischemia, or inflammation can cause stretching of unmyelinated fibers that innervate the walls or capsules of organs, resulting in visceral pain
Visceral pain is often described as “crampy, dull, or achy,” and it can be either steady or intermittent (colicky)
(Think obstruction).
Describe parietal pain
Parietal (somatic) abdominal pain is caused by irritation of myelinated fibers that innervate the parietal peritoneum, usually the portion covering the anterior abdominal wall.
This may be caused by continued inflammation from an obstructed organ or chemical irritants
Parietal afferent signals: specific area of peritoneum! Parietal pain can be localized to the dermatome superficial to the site of the painful stimulus.
If you think you need blood later on then what should you order
Type and Screen
If you need blood now, what should you order
Type and Cross
Who is it most common to have appendicitis
Acute appendicitis is most common in patients age 10 to 19 years, remains the most frequent cause of atraumatic abdominal pain in children >1 year old, and is the most common non-obstetric surgical emergency in pregnancy, complicating up to 1 in 1500 pregnancies.
What is the traditional cause of appendicitis
Luminal obstruction of the vermiform appendix, typically by a fecalith,(poop stone) is considered the traditional cause of appendicitis.
What is the location of McBurney’s point
located one third of the distance from the anterior superior iliac spine to the umbilicus.
What is the initial pain sensation of appendicitis
unenervated visceral pain fibers
What is rovsings sign
Rebound referred pain from contra lateral compression of the abdomen that is a sign of appendicitis
What kind of pyuria is present is appendicitis
Sterile pyuria
In appendicitis in pregnant or child pts
What is the imaging modality of choice
US ! First
What is the imaging for Appendicitis in the majority of pts
Non con ct
What is the tx for appendicitis
Immediate surg consult
NPO immediately
Maintenance fluids and pain meds
ABX as appropriate
Ampicillin/Sulbactam
Pipercillin/ Tazobactam
Cefetoxin
What is the flow of ducts through the pancreas
Bile flows out of the liver through the left and right hepatic ducts, which come together to form the common hepatic duct. This duct then joins with a duct connected to the gallbladder, called the cystic duct, to form the common bile duct. The common bile duct enters the small intestine at the sphincter of Oddi (a ring-shaped muscle), located a few inches below the stomach.
How does pancreatitis general resolve
Generally resolves with only supportive care
IV Fluids, pain control, bowel rest etc etc..
What are the common pancreatitis presentation in men vs women
Alcohol is more common in men
Gall stones more common in women
What surgery has a 5% incidence rate for pancreatitis
ERCP ( gall stone removal)
What enzyme is responsible for auto digestion of the pancreas
Trypsin
What is the criteria to Dz pancreatitis
(1) clinical presentation consistent with acute pancreatitis
(2) serum lipase or amylase elevated above the upper limit of normal (X3)
(3) imaging findings characteristic of acute pancreatitis
(IV contrast CT, MRI, or transabdominal US)
How elevated with the amylase or lipase be in pancreatitis
3x ULN
ALT elevated above 150 means..
An alanine aminotransferase of >150 U/L within the first 48 hours of symptoms predicts gallstone pancreatitis
When does pancreatitis show up on CT
72 hours of onset
What is the SIRS criteria for severe acute pancreatitis
Patient characteristics:
>55 years, obesity, AMS, comorbidities
Labs:
BUN >20 or rising; hematocrit >44% or rising; ↑creatinine- DEHYDRATION!
What is the treatment appraoch to biliary pancreatitis
Early surgical consult! ERCP
In a female, fat, fertile over 40
Think of what d/o
Cholecystitis
What is the most common complication of gallstone dz
Biliary colic
Define emphysemic cholecystitis
inflamed gallbladder becomes infected with gas-producing organisms
Define choleodocolithiasis
gallstones within the common bile duct
Define Cholangitis
Infection of the biliary tree
What is billary sludge
Biliary sludge is microlithiasis composed of cholesterol crystals, calcium bilirubinate pigment, and other calcium salts
Define acute acalculus cholesytisis
Occurs in the setting of critical illness such as septic shock, burns, & major trauma or surgery
Old age, DM, and immunosuppression are also risk factors
A pt that presents with N/V and back pain that happens around midnight
Think
Cholecystitis and biliary colic
Jaundice in the setting of biliary tract stone disease implies:
Obstruction of the CBD from choledocholithiasis
What is the Dx criteria for Acute cholecystitis
+ Murphys
RUQ pain
Fever, Elevated CRP And WBC
What is Charcots triad
Fever
RUQ abdominal pain
Jaundice
Dx cholangitis
What is Reynolds pentad
Fever
RUQ abdominal pain
Jaundice
+ AMS and Shock
For cholangitis
What is the most sensitive serum marker for choledocholithiasis
GGT
What is the normal measurement for the common bile duct
Less than 5cm
If youre looking for choledocholithiasis
What should you order
ERCP
What is the perferred initial imaging for cholecystitis
US
How do we tx biliary colic
Elective cholecystectomy is occasionally recommended for those at high risk for gallstone complications
- Sickle cell disease
- Planned organ transplantation
- Ethnic groups at high risk for GB cancer
ED managment of biliary colic:
NSAIDs 1st line, Antiemetics, analgesics
Referal to outpt or to general surgery
What is the tx approach to acute cholecytsis
Laparotomy/ scopy
Analgesics Antiemits NPA Fluids And ABX
What is a gallstone ileus
Gallstone ileus —>mechanical SBO caused by an ectopic gallstone that has reached the intestinal lumen via a biliary-enteric fistula
What is riglers triad
Diagnosed on plain films or with CT (usually) for gallstone ileus
Rigler’s triad: small bowel obstruction, pneumobilia, and an ectopic gallstone.
What separates upper and lower GI bleed
Ligament of tritz
What is the most common cause of GI bleeding
PUD
What is responsible for maintingin the gastric mucosal barrier
Prostaglandins
What is the major cause of varicela bleeding
Cirrhotics
What are the S/s of an underlying GI bleed
Hypotension, tachycardia, angina, syncope, weakness, confusion, or cardiac arrest
What is the most reliable way to Dx Upper GI bleed
Visual inspection of the vomitus
Spider angiomas, palmar erythema, jaundice, and gynecomastia suggest
Liver Dz
What is the single most important lab test for a signifigant bleed
Cross and match
What is the BUN level be in an upper GI bleed
Elevated
An elevated lactate level is a sentinel sign of…
Severe illness
Can pts with GI bleeds get barium studies
Barium contrast studies are contraindicated because barium may hinder subsequent endoscopy or angiography- don’t do them
When should you order tagged red blood cells
In babies or in pts with C/i for endoscopy
What procedure is both Dx and Tx for a GI bleed
NG placement and aspiration are diagnostic and therapeutic
What is the threshold for blood transfusion in a GI bleed
Transfusion is less than 7 or less than 9 in older pts
What is the ABX for prophylaxis in Upper GI bleed
Ciprofloxacin 400 mg
Or Ceftriaxone 1 gram IV
Only really need for pts with cirrhosis
What is a concerning INR in a pt with a GI bleed
INR ≥1.5 is a significant predictor of mortality in UGIB pts who are receiving anticoagulants! They are thin!!!
What is octreotide used for in an Upper GI Bleed
Octreotide is a long-acting analog of somatostatin that elicits several actions in patients with UGIB
Inhibits the secretion of gastric acid- good
Reduces blood flow to the gastroduodenal mucosa- also good
Causes splanchnic vasoconstriction- Mixed..
If a pt has an allergy to ciprofloxacin what is the ABX to be used
Ceftriaxone
When should we use ABX in a Upper GI Bleed
Patients with cirrhosis have an impaired immune system and have an increased risk of gut bacterial translocation during an acute bleeding episode
Prophylactic antibiotics
- Reduce infectious complications
- May decrease mortality
- Start ASAP
- Ciprofloxacin 400 mg IV or ceftriaxone 1 gram IV
What is the Dx study of choice in a Uppe GI bleed
UGI endoscopy is the diagnostic study of choice for bleeding- Why?
Allows visualization of bleeding source (in most cases) & administration of hemostatic therapy- two in one!
What is the most common cause of Lower GI bleed
diverticular disease
Define hematochezia
bright red or maroon-colored rectal bleeding
Originating from a UGI source—> brisk UGIB
May be accompanied by hematemesis & hemodynamic instability
~10% of hematochezia episodes may be associated with UGIB
Define Melena
Melena—> dark or black-colored stools
Usually represents bleeding from a UGI source
May also represent slow bleeding from an LGI source along with slow colonic transit or constipation..
Is bleeding from diverticulosis painful?
Usually painless
Describe Vascular ectasia
Incl. arteriovenous malformations & angiodysplasias of the colon
Can also be present in the small bowel
Development in the large bowel —> chronic process & increases with age
Valvular heart disease is a risk factor for developing bleeding vascular ectasias
What is the most common cause of intestinal ischemia
Ischemic colitis
What are the pts for high index for ischemia and Mesenteric ischemia
> 60 years old
Atrial fibrillation
Congestive heart failure
Recent myocardial infarction
Postprandial abdominal pain
Unexplained weight loss
What is the Dx study of choice for Ischemic and Mesenteric ischemia
Angiography
Describe meckels diverticulum
Consists of embryonic tissue
Most commonly found in the terminal ileum
More than half of lesions contain ectopic gastric tissue
Can secrete gastric enzymes, eroding the mucosal wall & cause bleeding
Rare but important condition, esp in the younger population!
Bleeding and a non tender abdomen is a sign of..
Nontender abdomen (predictive of severe bleeding)
LGIB, a lack of abdominal tenderness suggests bleeding from disorders involving the vasculature (diverticulosis or angiodysplasia)
What is the BUN in a upper or lower GI bleed
Bleeding from a source higher in the GI tract may elevate blood urea nitrogen levels through digestion & absorption of hemoglobin
Which is more sensitive for a bleed in the GI
Scintigraphy or angiography
Scintigraphy appears more sensitive than angiography and can localize the site of bleeding at as low a rate as 0.1 mL/min
What is the role of multi detector CT angiography
Multidetector CT angiography has a sensitivity up to 100% and specificity of up to 99% for detecting active or recent GI bleeding
~93% accurate in determining the site of bleeding
Useful tool prior to treatment with conventional angiography
What is the tole or flexible sig
Can evaluate possible distal colonic & rectal sources of bleeding
Cannot identify more proximal sources of bleeding
If colonoscopy fails to determine the source of bleeding—>consider…
onsider upper endoscopy to evaluate for a UGI source
Describe diverticulitis
Incidental finding
small herniations at sites where the vasculature (vasa recta) penetrates the circular muscle layer of the colon
True diverticula involve all layers of the colon wall