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Biomedical Science 1 > Early Tooth Development > Flashcards

Early Tooth Development Flashcards

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Biology 101 flashcards
1
Q

What are the 3 overlapping phases of tooth development?

A
  1. Initiation
  2. Morphogenesis
  3. Histogenesis
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2
Q

What 2 things occur during the initiation phase of odontogenesis?

A
  1. Site of future teeth established

2. Appearance of tooth germ

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3
Q

What occurs during the morphogenesis phase of odontogenesis?

A

Shape of teeth are determined by cell proliferation and movement

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4
Q

What occurs during the histogenesis phase of odontogenesis?

A

Differentiation of cells give rise to all dental tissues

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5
Q

At what age does tooth development begin?

A

6 weeks in utero

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6
Q

Where are teeth derived from?

A

Ectoderm and mesoderm with contribution from neural crest cells

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7
Q

What are neural crest cells?

A

Specialised group of migratory cells which originate from neuroectoderm

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8
Q

What is the main function of NCCs?

A

Essential for the formation of most of the CT elements found in the head

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9
Q

What is the stomodeum?

A

Primitive mouth lined by ectoderm

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10
Q

What occurs in the initiation phase at 6 weeks in utero?

A

Oral epithelium of stomodeum thickens and invaginates to form primary epithelial band

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11
Q

What is the primary epithelial band?

A

Horseshoe-shaped band which correspond roughly to shape of future dental arches

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12
Q

What does the primary epithelial band divide into?

A
  1. Vestibular lamina

2. Dental lamina

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13
Q

What does the vestibular lamina go on to form?

A

Vestibule between cheek and tooth-bearing area

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14
Q

What does the dental lamina contribute to the formation of?

A

Teeth

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15
Q

What occurs at 8 weeks in utero during the morphogenesis stage of tooth development?

A

Dental lamina lengthens and forms swellings of epithelium surrounded by condensation of ectomesenchymal cells

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16
Q

What do the epithelial swelling and ectomesenchymal cells make up?

A

Tooth germs

17
Q

What are the 3 stages that tooth germs can be classified into?

A
  1. Bud stage
  2. Cap stage
  3. Bell stage
18
Q

What occurs during the bud stage?

A

Extensive proliferation of dental lamina into buds

19
Q

What is the term given to the tooth germ once the bud stage occurs?

A

Enamel organ

20
Q

How many buds will be present in each arch?

A

10

21
Q

What 2 main things occur during the cap stage?

A
  1. Proliferation of the cells of the enamel organ

2. Deeper surface of enamel organ invaginates

22
Q

What 4 major structures are present in the cap stage?

A
  1. Enamel organ
  2. Dental papilla
  3. Dental sac
  4. Stella reticulum
23
Q

What is the enamel organ?

A

Formation of tooth bud In a cap shape with a deep central impression

24
Q

What is the dental papilla?

A

Condensed mass of ectomesenchyme within the concavity of the enamel organ

25
Q

What is the dental sac?

A

Condensed mass of ectomesenchyme surrounding the outside of the enamel organ

26
Q

What is the stellate reticulum?

A

Cells in the centre of the enamel organ which have separated and accumulated GAGs in between

27
Q

What 2 things occur during the early bell stage?

A
  1. Dental lamina breaks down and enamel organ loses contact with oral epithelium
  2. Dental lamina between tooth germs degenerate
28
Q

What are the two types of tissues in the dental papilla during the early bell stage?

A
  1. Odontoblasts

2. Primordium of the pulp

29
Q

What occurs during the late bell stage?

A

Apposition stage - Formation of hard dental tissues

30
Q

How do ameloblasts arise?

A

Internal enamel epithelium lines along basement membrane and differentiates into preameloblasts which in turn differentiate into ameloblasts

31
Q

How do odontoblasts arise?

A

Outer cells of dental papilla differentiate into odontoblasts

32
Q

What are the 6 main bell stage structures?

A
  1. Dental follicle
  2. External enamel epithelium
  3. Stellate reticulum
  4. Stratum intermedium
  5. Internal enamel epithelium
  6. Dental papilla
33
Q

At what stage do small blood vessels invade the dental papilla?

A

Early bell stage

34
Q

At what stage do nerve fibres form a plexus below the dental papilla?

A

Cap stage

Biomedical Science 1 (19 decks)

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