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Immunology > E1-Lymph > Flashcards

E1-Lymph Flashcards

1
Q

REVIEW: Origin of Lymph Cells in embryology?

A

Yolk Sac Islands

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2
Q

What are the two primary Lymphoid Organs?

A

1.Thymus 2. Bursa of Fabricus

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3
Q

Since we are not birds where are B cells developed in Mammals?

A

Bursa Equivalent

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4
Q

What are the 4 places of Bursa Equivalent?

A
  1. GALT (Gut Associated Lymphoid Tissue) 2. Tonsils 3. Peyers Patches of the ileum 4. appendix
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5
Q

What are the 3 secondary Lymphoid organs?

A

1.Lymph Nodes 2.Spleen 3. GALT(Gut Associated Lymphood Tissue)

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6
Q

What are the QB cells of inflammation? What do they “pass out”?

A

T-Cell Lymphocytes, pass out lymphokines

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7
Q

What are the mediators of Humoral Immunity?

A

Antibodies from B-Cells

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8
Q

What is parenchyma?

A

Functional Lymphoid Tissue

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9
Q

Diffuse lymph tissue = ?

A

T-cells!

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10
Q

Nodular Lymph tissue = ?

A

B-cells!

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11
Q

What are the two components to a nodule?

A

light central Germinal Center, darker surrounding cap

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12
Q

Are there reticular fibers in primary lymphoid organs? AKA is there nodular tissue in PRIMARY lymphoid organs?

A

NO. DIFFUSE ONLY (T-Cells). (no b-cell nodules)

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13
Q

Does the secondary lymph organ contain diffuse and nodular tissue?

A

YES! diffuse=T, nodular =B

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14
Q

Why is the medulla of the thymus “lighter” in appearance?

A

Because its only Diffuse tissue! (no “thick” nodules)

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15
Q

What corpuscles are unique to the THYMUS ONLY? What veggie is used to describe them?

A

HASSAL’s Corpuscles! AN onion!

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16
Q

What might be the function of the corpuscles in the Thymus?

A

Hassal’s corpuscles might take part in t cell death

17
Q

What is the substance in the cortex of the thymus that generates t lymphocytes? (logical name!)

A

Thymo-Poietin

18
Q

What happens to Hassal’s corpuscles in the thymus once the thymus starts to die at puberty?

A

Hassal’s Corpuscles ENLARGED (adipose tissue)

19
Q

What is the PRIMARY lymphoid organ where the Bursa Equivalent resides? (The rest of Bursa Equivalent are in secondary lymphoid tissues)

A

GALT (Gut Associate Lymphoid Tissue)

20
Q

Where are nodules in lymph nodes? Where is the diffuse tissue in lymph nodes?

A

B-cell nodules in the cortex…T-cell diffuse in the medulla

21
Q

What is the concave aspect of a lymph node that is thick Connective Tissue? What is found here?

A

HILUS..Blood Supply to Lymph node

22
Q

What is the main structural substance of the lymph node medulla? What type of WBC is found here?

A

Cord (AKA sinus!)! Macrophages!

23
Q

Where does lymph ultimately end up after going through lymph nodes?

A

the neck region/venous circulation

24
Q

What two cells remove 99% of impurities in lymph nodes?

A

Macrophages and Dendritic Cells

25
Q

What is the largest lymphoid organ in the body?

A

the spleen!

26
Q

What is the convex portion of the spleen with Blood supply? (think lymph node!)

A

HILUS

27
Q

White pulp of spleen

A

PALS, DIFFUSE T-CELL

28
Q

Red pulp of spleen

A

Sinuses and Cords w/ trapped RBCs (Diffuse and Nodular)

29
Q

What is the DIFFUSE tissue that surrounds arteries in the spleen? What type of tissue extends off of this?

A

PALS (PeriArteriolar Lymphoid Sheath)=DIFFUSE T-Cells=WHITE PULP…Nodular tissue extends off of it!

30
Q

What “zones” are between the red and white pulp? FXN?

A

Marginal Zones. Receive the blood and trap antigens

31
Q

How many pyres patches are there?

A

30-40

32
Q

What are the 5 oral tonsils?

A

2 Palatine, 2 lingual, and 1 pharyngeal

33
Q

What are the “deep” stratified squamous structures of the tonsils?

A

Crypts

34
Q

Do the tonsils have the same frame work as a lymph node?

A

Yes, b-cell cortex and t-cell medulla

35
Q

Where is the appendix? Does it have the same structure as lymph nodes and tonsils?

A

the cecum. yes, b-cell cortex and t-cell medulla

Immunology (10 decks)

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