E1-Clinical Immunology (minus Complement Sys) Flashcards
Active Immunity vs Passive Immunity
Active: Memory with TCells Passive: Exogenous Antibodies
BOARDS: What is the poster child Acute Phase Reactant? What are the two products of this poster child? WHAT organ do they come from?
CYTOKINES!–>Interleukins, Tumor Necrosis Factor-aplha…The LIVER!
What are these proteins categorized as?: C-Reactive, Complement factors, Plasminogen, Alpha-1-AntiTrypsin, Serum Amyloid A, Firbrinogen, Prothrombin, Alpha-2-MacroGlobulim…
Types of Acute Phase Reatants
What are glycoproteins that inhibit the spread of VIRUSES?
Interferons
What are the two cells of the acquired(adaptive) immunity?
T and B lymphocytes
What are the hallmark cells of chronic inflammation?
Lymphocytes!
What is the abbreviated name for “helper T cells”?
CD4
What is the abbreviated name for “cytotoxic T cells”? what type of pathogen is the main target?
CD8, Viruses
What are the first antibodies to appear in primary response?
IgM
What are the 4 types of immune mechanisms?
I: Anaphylaxis/Immediate Hypersensativity II:Cytotoxic Antibody Reactions (Complement) III: Immune Complex Mediated Reations IV:Cell Mediated Reactions
Which type of immune response involves BradyKinin, Histamine, SRS-A, and Hives?
TYPE I: Anaphylaxis/Immediate Hypersensitivity
Does anything happen on 1st exposure with Type I: Anaphylaxis/Immediate Hypersensitivity?
No, just IgE binds. Second exposure is when it gets nasty
What are pruritic erematous plaques resulting from localized MAST cell degranulation?
Wheals
What Type I reaction results in EGG like swelling? ALSO TONGUE/LARYNGEAL SWELLING!!
Angiodema
What other Type I causes laryngeal swelling?
Anaphylaxis
Which type include mismatched blood transfusions, Goodpasture Syndrome, and Erythroblastosis?
Type II
What type is LUPUS, Rheumatoid Arthritis associated with?
Type III
What type is TB, Fungal Disease, and Contact Dermatitis, granuloma involved in?
Type IV
