E1-Clinical Immunology (minus Complement Sys) Flashcards
Active Immunity vs Passive Immunity
Active: Memory with TCells Passive: Exogenous Antibodies
BOARDS: What is the poster child Acute Phase Reactant? What are the two products of this poster child? WHAT organ do they come from?
CYTOKINES!–>Interleukins, Tumor Necrosis Factor-aplha…The LIVER!
What are these proteins categorized as?: C-Reactive, Complement factors, Plasminogen, Alpha-1-AntiTrypsin, Serum Amyloid A, Firbrinogen, Prothrombin, Alpha-2-MacroGlobulim…
Types of Acute Phase Reatants
What are glycoproteins that inhibit the spread of VIRUSES?
Interferons
What are the two cells of the acquired(adaptive) immunity?
T and B lymphocytes
What are the hallmark cells of chronic inflammation?
Lymphocytes!
What is the abbreviated name for “helper T cells”?
CD4
What is the abbreviated name for “cytotoxic T cells”? what type of pathogen is the main target?
CD8, Viruses
What are the first antibodies to appear in primary response?
IgM
What are the 4 types of immune mechanisms?
I: Anaphylaxis/Immediate Hypersensativity II:Cytotoxic Antibody Reactions (Complement) III: Immune Complex Mediated Reations IV:Cell Mediated Reactions
Which type of immune response involves BradyKinin, Histamine, SRS-A, and Hives?
TYPE I: Anaphylaxis/Immediate Hypersensitivity
Does anything happen on 1st exposure with Type I: Anaphylaxis/Immediate Hypersensitivity?
No, just IgE binds. Second exposure is when it gets nasty
What are pruritic erematous plaques resulting from localized MAST cell degranulation?
Wheals
What Type I reaction results in EGG like swelling? ALSO TONGUE/LARYNGEAL SWELLING!!
Angiodema
What other Type I causes laryngeal swelling?
Anaphylaxis
