drugs in pregnancy Flashcards
What is pharmacokinetics
What the body does to the drug
What is pharmacodynamics
What the drug does to the body
What is the treatment of nausea and vomiting in pregnancy
First line:
Cyclizine
Prochloroperazine
doxylamine/pyridoxine
Second line:
ondansetron
metocloperamide
What is the treatment for hypertension in a pregnant women
labetolol
nifedipine
methyldopa
hydralazine
What are teratogenic hypertensive medication which shouldn’t be given to pregnant women
ACE inhibitors
Angiotensin receptor antagonists
What are the safest epileptic medication during pregnancy
carbamazepine
lamotrigine
What does phenobarbitone cause to a baby when taken by a pregnant mother
Cardiac malformations
What does sodium valproate do to a baby after mother took it during pregnancy
NTD - neural tube defects W
facial clefts
What should be given with epileptic medication in pregnancy
High dose folic acid
What are the drugs indicated for diabetes in pregnancy
Insulin and metformin
What can be given for a thromboembolism during pregnancy
Low molecular weight heparin
What does warfarin do when a pregnant mother takes it
Fetal warfarin syndrome and fetal embryopath: nasal hypoplasia,= and skeletal abnormalities such as short limbs and digits and stippled epiphyses
What is the treatment for asthma in a pregnant mother
B2 agonist - Dibuterol and salbutamol
Inhaled corticosteroid - budesonide
Systemic corticosteroids if the asthma is severe
What is the treatment given to pregnant women during headaches and migraines
Paracetamol
Ibuprofen but avoid in 3rd trimester
Sumatriptan - acute treatment for migraine
Propanolol in the lowest effective dose
What are the risks when giving morphine based medication to a pregnant mother
No increase in congenital abnormalities but there is a risk of neonatal respiratory depression and with drawl
