Drugs for Thyroid Conditions (week 7)

Question 1

Name a Thyroid Drug

Answer 1

Levothyroxine (Synthroid)

Question 2

What is the MOA of Levothyroxine (Synthroid)?

Answer 2

Synthetic Thyroxine (T hormone)

Question 3

What are the Common adverse effects of Levothyroxine (Synthroid)?

Answer 3

Palpitations
Nervouseness
Insomnia
Diarrhea
Weight loss

Question 4

What are the Serious adverse effects of Levothyroxine (Synthroid)

Answer 4

Hyperthyroidism 
Tachycardia 
Angina 
MI
Bone loss

Question 5

What does Levothyroxine (Synthroid) interact with?

Answer 5

Proton Pump Inhibitors

Antacids

Question 6

How should you dose Levothyroxine (Synthroid)?

Answer 6

Start low go slow (2 week intervals)

Question 7

What should you tell a patient to report when taking Levothyroxine (Synthroid)?

Answer 7

Chest Pain
Heart Palpitations
Insomnia

Question 8

Name an antithyroid

Answer 8

Methimazole

Question 9

What is the MOA of Methimazole?

Answer 9

Prevents the oxidation of iodide and prevents iodinated tyrosine from coupling

Question 10

What are the adverse effects of Methimazole?

Answer 10

Rash
Arthritis

Agranulocytosis
Vasculitis
Pancreatitis
hepatotoxicity

Question 11

How long does it take for Methimazole to reach therapeutic levels?

Answer 11

3 to 12 weeks

Question 12

When should you take Methimazole?

Answer 12

Once daily, at the same time everyday