Bronchodilators (week 5)

Question 1

Where are the Beta 2 Adrenergic Receptors located?

Answer 1

Lungs
Uterus
Select arterioles
Liver
Skeletal Muscle

Question 2

Where does bronchial dilation occur?

Answer 2

Lungs

Question 3

Name a Short Acting Beta2 Agonist (SABA)

Answer 3

Albuterol

Question 4

What is Albuterol used for?

Answer 4

Quick-relief agent for acute bronchospasm

Question 5

What is the action of Albuterol?

Answer 5

Stimulate B2 adrenergic receptors in the smooth muscle of bronchi and bronchioles, promoting bronchodilation

Question 6

What can Albuterol initially cause?

Answer 6

Bronchospasm

Question 7

What should you assess before administering Albuterol?

Answer 7

Trigger factors, caffeine intake
MAR: Beta blockers, thyroid hormones
PMH: Use of systemic Beta Agonist with DM, Hyperthyroidism, and HTN

Question 8

What medicine should you use before other inhalants?

Answer 8

Albuterol

Question 9

Name a Long-Acting Beta2 Agonist (LABA)

Answer 9

Salmeterol (Serevent diskus)

Question 10

How often should you use Salmeterol (Serevent Diskus)?

Answer 10

Every 12 hours

Question 11

What is the MOA of Salmeterol (Serevent diskus)?

Answer 11

Produces accumilation of cAMP

Question 12

What is Salmeterol used for?

Answer 12

Asthma controller, not first choice never use alone

Question 13

Name a Xanthine

Answer 13

Theophylline (elixophyllin)

Question 14

What is the MOA of Theophylline (elixophyllin)?

Answer 14

Relax smooth muscles of bronchi by backing receptors for adenosine

Question 15

What is the use of Theophylline (elixophyllin)?

Answer 15

Second-line agent for long-term control

Question 16

What are some severe adverse effects of Theophylline (elixophyllin)?

Answer 16

AFib
Tachyarrhythmia
Seizures

Question 17

What kind of interactions does Theophylline (elixophyllin) have?

Answer 17

Multiple drug-drug

Caffeine

Question 18

Name an Anticholinergic

Answer 18

Ipratropium (Atrovent)

Question 19

What is the MOA of Ipratropium (Atrovent)?

Answer 19

Prevents Bronchoconstriction

Question 20

What Ipratropium (Atrovent) used for?

Answer 20

Maintenance therapy of reversible airway obstruction due to COPD

Question 21

What drugs fo you use to manage Stable COPD?

Answer 21

LABA
LAMA
ICS
PDE4

Question 22

What drugs do you use to manage COPD Exacerbations?

Answer 22

SABA
SAMA
Systemic glucocorticoids
Antibiotics
Supplemental Oxygen

Question 23

What are the two treatment goals for COPD?

Answer 23

Reduce symptoms

Reduce risks and mortality

Question 24

What are the upper respiratory drugs?

Answer 24

Intranasal glucocorticoids
Antihistamines
Decongestants
Antitussives
Expectorants
Mucolytics

Question 25

What are the two treatment goals for asthma?

Answer 25

Reducing impairment

Reducing risk

Question 26

What is the most used combination medications for asthma/COPD?

Answer 26

Long acting beta-agonist and corticosteroid

Question 27

Name a Long-Acting Antimuscarinic Antagonist (LAMA)

Answer 27

Tiotropium (Spiriva) Inahaltion

Question 28

What is the MOA of Tiotropium?

Answer 28

Acts as anticholinergic by selectively and reversibly inhibiting M3 receptors in smooth muscle in airways

Question 29

What is Tiotropium used for?

Answer 29

Maintenance therapy of bronchoconstriction associated with Chronic Bronchitis and Emphysema

Question 30

What are some serious adverse effects of Tiotropium?

Answer 30

Angioedema
Urinary retention
Bowel obstruction