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Pharm Test 2 > Beta-Lactam Antibacterial Agents (week 6) > Flashcards

Beta-Lactam Antibacterial Agents (week 6) Flashcards

1
Q

What are the 4 Beta-Lactam Antibacterial Agents?

A

Penicillins
Cephalosporins
Carbapenems
Monobactams

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2
Q

If someone is anaphylactic, what drug do you not give?

A

Beta-Lactum Antibacterial Agents

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3
Q

What is Penicillin (Ampicillin) used for?

A

Gram-positive bacteria

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4
Q

What are the adverse effects from Pencillin (Ampicillin)?

A

Diarrhea
Rash
Urticaria

Allergic reaction
C.Diff

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5
Q

What are some baseline info you want to know before administering Penicillin (Ampicillin)?

A

Cultures

PMH of allergic reaction to other Beta Lactams (Anaphylactic reactions)
History of Mono

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6
Q

How should you administer Penicillin (Ampicillin)?

A

Oral, 1 hour before or 2 hours after meals

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7
Q

What do you want to evaluate for after administering Penicillin (Ampicillin)?

A

Kidney Function

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8
Q

What are the Beta-lactamase Inhibitors?

A

Clavulanate
Sulbactam
Tazobactam

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9
Q

What Generation is Cefazolin (Ancef)?

A

1st gen Cephalosporin

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10
Q

What is the use of Cefazolin (Ancef)?

A

Gram-positive coverage

Given Pre-op Prophylaxis

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11
Q

How is Cefazolin (Ancef) Given?

A

IM, IV

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12
Q

Where is Cefazolin (Ancef) metabolized?

A

Not the liver

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13
Q

What are some serious side affects of Cefazolin (Ancef)?

A

Leukpenia
Neutropenia
Thrombocytopenia

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14
Q

What are some baseline info you want to know before administering Cefazolin (Ancef)?

A 
Culture samples
Drug class includes 5 subgroups

PMH os severe allergic reaction to other Beta Lactams

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15
Q

How id Cefazolin (Ancef) administered?

A

Orally with meals
IM
IV Piggyback

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16
Q

Name a Carbapenem

A

Imipenem-cilastatin (Primaxin)

17
Q

What is Imipenem-Cilastatin (Primaxin) used for?

A

Has an extremely broad spectrum

18
Q

How is Imipenem-Cilastatin (Primaxin) administered?

A

IM

IV

19
Q

What are the common adverse effects of Imipenem-Cilastatin (Primaxin)?

A

Diarrhea
Nausea
Vomiting
Rash

20
Q

What are some serious side effects o fImipenem-Cilastatin (Primaxin)?

A

CNS depression

Seizures

21
Q

What are some contraindications for Imipenem-Cilastatin (Primaxin)?

A

Cephalosporins (Cefazolin)

22
Q

What does Imipenem-Cilastatin (Primaxin) interact with?

A

Probenecid
Cyclosporine
VALPORIC ACID!

23
Q

Name a Glycopeptide

A

Vancomycin

24
Q

What is Vancomycin used for?

A

Gram positive bacteria
C. Diff
MRSA

25
Q

How is Vancomycin administered?

A 
IV piggyback (slowly)
PO
26
Q

What are some common adverse effects for vancomycin?

A

Thrombophlebitis

27
Q

What are some serious adverse effects for vancomycin?

A

Renal Failure

Ototoxicity

28
Q

What are some baseline info you want to know before administering Vancomycin?

A

Check serum trough levels

PMH of renal impairment or previous hearing loss

29
Q

Name a monbactam

A

Aztreanam (Azactam)

30
Q

What is Aztreanam (Azactam) used for?

A

Serious gram-negative infections

31
Q

How is Aztreanam (Azactam) given?

A

IM
IV
Inhalin

32
Q

What are some adverse effects of Aztreanam (Azactam)?

A

Upper airway imitation
Chest discomfort
Cough/Wheezing

Seizures
Anaphylaxis

Pharm Test 2 (18 decks)

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