Bacteriostatic Inhibit Protein Synthesis (week 6)

Question 1

What are Tetracyclines used for?

Answer 1

Mycoplasma
Chlamydia
Acne
PCN Allergy

Question 2

What is the MOA of Tetracyclines?

Answer 2

Binds with 3OS ribosomes and inhibits microbial protein synthesis

Question 3

How are Tetracyclines administered?

Answer 3

PO

Question 4

What are some adverse effects of Tetracyclines?

Answer 4

Diarrhea
Nausea
Vomiting
Photosensitivity

Esophagitis
Discoloration of teeth
Interference with bone growth

Question 5

What are some things you want to know before administering Tetracycline?

Answer 5

PMH of pregnancy, significant renal impairment

Question 6

Name a Macrolide

Answer 6

Erythromycin

Question 7

What is Erythromycin considered a substitute for?

Answer 7

PCN (Penicillin)

Question 8

What is the MOA of Erythromycin?

Answer 8

Suppresses protein synthesis at the level of the 50S bacterial ribosome

Question 9

What are some adverse effects of erythromycin?

Answer 9

Nausea
Vomiting
Phlebitis
Rash

Ototoxicity

Question 10

What are some things you want to know before administering Erythromycin?

Answer 10

PMH of hypersensitivity

MAR: taking inhibitors of CYP3A4

Question 11

How is erythromycin adminstered?

Answer 11

PO, IV

Take on an empty stomach