Basic Principles of Antimicrobial Therapy (week 6)

Question 1

Targets gram negatives and gram positives

Answer 1

Narrow Spectrum

Question 2

Carries gram positives and gram negatives

Answer 2

Broad spectrum

Question 3

Name Narrow Spectrum Antibiotics

Answer 3

Penicillin G & V
Oxacillin
Nafcillin
Vancomycin
Erythromycin
Clindamycin
Gentamycin 
Cephalosporins

Question 4

Name Broad Spectrum Antibiotics

Answer 4

Ampicillin 
Piperacillin
Cephalosporins (3rd and 5th gen)
Tetracycline
Imipenem 
Fluoroquinolones

Question 5

Staph, Strep, Enterococcus

Answer 5

Gram Positive Cocci

Question 6

Neisseria Gonorrhea

Answer 6

Gram Negative Cocci

Question 7

C. Diff

Answer 7

Gram Positive Bacilli

Question 8

E. coli, klebsiella pneumonia

Answer 8

Enteric gram-negative Bacilli

Question 9

Influenza, H. Pylori

Answer 9

Gram-negative bacilli

Question 10

What are the two mechanisms that cause drug resistance?

Answer 10

Spontaneous mutations

Conjugation

Question 11

Name a super infection

Answer 11

Yeast infection

Question 12

How do antibiotics promote drug resistance?

Answer 12

Broad-spectrum

Extent of use

Question 13

What is the most preferred testing when trying to select an antibiotic?

Answer 13

Empiric treatment

Question 14

What are the two ways to determine drug susceptibility?

Answer 14

Minimum inhibitory concentration (MIC)

Minimum bactericidal concentration (MBC)

Question 15

What is the most common way that antibiotics are misused?

Answer 15

Attempted treatment of viral infections

Question 16

What are other ways that antibiotics are misused?

Answer 16

Treatment of fever of unknown origin

Improper dosage

Question 17

What are the different ways that penetration of antibiotics can be impeded?

Answer 17

Meningitis (blood-brain barrier)
An infected abscess
Endocarditis