Drugs for Arrhythmias Flashcards
Procainamide
Class 1A sodium channel blocker
- sustained V Tach and arrhythmias associated with MI
Quinidine
Class 1A sodium channel blocker
- rarely used
Disopyramide
Class 1A sodium channel blocker
- recurrent ventricular arrhythmias
Lidocaine
Class 1B sodium channel blocker
- termination of V Tach in acute myocardial ischemia
Mexiletine
Class 1B sodium channel blocker
- ventricular arrhythmias
- relief of chronic pain (esp. due to diabetic neuropathy and nerve injury)
Flecainide
Class 1C sodium channel blocker
- pts with otherwise normal hearts who have supraventricular arrhythmias
Propafenone
Class 1C sodium channel blocker
- supraventricular arrhythmias in pts w/o structural dz
Esmolol
Class 2 Beta Blocker
- supraventricular tachy
- arrhythmias associated with thyrotoxicosis
- MI or acute MI with arrhythmias
- adjunct drug in general anesthesia to control arrhythmias during op.
Amiodarone
Class 3 K+ Channel Blocker
- recurrent ventricular tachycardia
- A fib
Sotalol
Class 2 non-selective Beta Blocker and Class 3 Agent that prolongs ADP
- life-threatening ventricular arrhythmias
- maintenance of sinus rhythm in pts with a fib
Dofetilide
Class 3 K+ Channel Blocker
- restore sinus rhythm in a fib pts
- maintain sinus rhythm after cardioversion in a fib pts
Ibutilide
Class 3 K+ Channel Blocker
- conversion of a flutter and a fib to sinus
Verapamil
Class 4 Ca2+ Channel Blocker
- termination and prevention of paroxysmal supraventricular tachycardia
- ventricular rate control in a fib and a flutter
Diltiazem
Class 4 Ca2+ Channel Blocker
- termination and prevention of paroxysmal supraventricular tachycardia
- ventricular rate control in a fib and a flutter
Adenosine
Miscellaneous Agent that activates K+ current and inhibits Ca2+ and funny currents
- conversion to sinus rhythm in paroxysmal supraventricular tachycardia
