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Maddy - CPR I - some pharm > Lipid Drugs > Flashcards

Lipid Drugs Flashcards

1
Q

atorvastatin

A

statin

- one of the strongest statins

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2
Q

fluvastatin

A

statin

- decreases LDL

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3
Q

lovastatin

A

statin

- decreases LDL

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4
Q

pitavastatin

A

statin

- not metabolized by CYP450

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5
Q

pravastatin

A

statin

- not metabolized by CYP450

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6
Q

rosuvastatin

A

statin

- one of the strongest statins

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7
Q

simvastatin

A

statin

- decreases LDL

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8
Q

nicotinic acid, vitamin B3

A

niacin

- increases HDL the most

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9
Q

fenofibrate

A

fibrate (fibric acid derivative)

- agonist for PPARa to regulate lipoprotein structure and function

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10
Q

gemfibrozil

A

fibrate (fibric acid derivative)

- agonist for PPARa to regulate lipoprotein structure and function

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11
Q

cholestyramine

A

resin (bile acid sequestran)

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12
Q

colesevelam

A

resin (bile acid sequestran)

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13
Q

colestipol

A

resin (bile acid sequestran)

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14
Q

ezetimibe

A

cholesterol absorption inhibitor

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15
Q

lomitapide

A

new treatment

- inhibits MTP which assembles apo-B, reducing chylomicrons, VLDL, and LDL

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16
Q

mipomersen

A

new treatment

- blocks apo-B

17
Q

evolucamab

A

new treatment, nothing else specified other than drug for lipid disorder

18
Q

alirocumab

A

new treatment, nothing else specified other than drug for lipid disorder

Maddy - CPR I - some pharm (25 decks)

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