Drugs for Amoiebiasis

Question 1

tissue (bowel wall and liver) amoebicides (4)

Answer 1

chloroquine
emetines
metronidazole
tinidazole

Question 2

luminal amebicides(3)

Answer 2

diloxanide furoate
iodoquinol
paromomycin

Question 3

asymptomatic intestinal amoeba infection DOC

Answer 3

diloxanide furoate

alternative: iodoquinol, paromomycin

Question 4

DOC for mild to moderate intestinal amoeba infection

Answer 4

metronidazole plus luminal agent (diloxanide furoate
iodoquinol
paromomycin)

Question 5

DOC for severe intestinal infection

Answer 5

metronidazole or tinidazole plus luminal agent

Question 6

DOC for hepatic amoebic abscess and other extraintestinal disease

Answer 6

metronidazole or tinidazole plus luminal agent

Question 7

First line drug for early west african trypanosomiasis

Answer 7

Pentamidine

Question 8

First line drug for west african trypanosomiasis with CNS involvement

Answer 8

eflornithine

Question 9

First line drug for early east african trypanosomiasis

Answer 9

suramin

Question 10

First line drug for east african trypanosomiasis with CNS involvement

Answer 10

melarsoprol

Question 11

DOC for african sleeping sickness

Answer 11

melarsoprol

Question 12

DOC for chagas disease

Answer 12

nifurtimox