Antimalarials

Question 1

tissue (liver schizontozides) (2)

Answer 1

primaquine

atovaquone

Question 2

blood (erythrocyte) schizontozides

Answer 2

chloroquine
quinine
mefloquine
atovaquone
pyrimethamine
doxycycline
halofantrine
artemisinin

Question 3

Gametocide

Answer 3

primaquine

Question 4

sporontocide (2)

Answer 4

proguanil
pyrimethamine

(prevents sporogony and multiplication in the mosquito

Question 5

DOC for chloroquine-sensitive P faliciparum

Answer 5

Chrloroquine

Question 6

DOC for P. vivax and ovale

Answer 6

Chloroquine then Primaquine

Question 7

uncomplicated chroroquine-resistant P. faciparum

Answer 7

Artemether + Lumefantrine (Coartem)

Alternative
Malarone or Mefloquine or Quinine Sulfate + Clindamycin or other Artemisinin-based combination drugs

Question 8

Severe or complicated P. falciparum

Answer 8

Artesunate then Doxycycline or Clindamycin or CoArtem; Quinidine gluconate

Alternative: artemether or quinine dihydrochloride

Question 9

DOC for malaria in pregnant patients

Answer 9

quinine

Question 10

DOC for uncomplicated falciparum in the Philippines

Answer 10

Co artem

Question 11

chemoprophylaxis for malaria

chloroquine-sensitive areas

Answer 11

chloroquine 500mg/tab 1 tab weekly

Question 12

chemoprophylaxis for malaria

chloroquine-resistant areas

Answer 12

mefloquine 250mg/tab 1 tab weekly or

malarone (atovaquone 250/proguanil 100) 1 tab daily

Question 13

chemoprophylaxis for malaria

multi-drug resistant areas

Answer 13

doxycyline 100 mg/tab 1 tab daily

Question 14

chemoprophylaxis for malaria

P. vivax, and P. ovale

Answer 14

Primaquine 30 mg daily for 2 weeks