Antifungal Drugs Flashcards
1
Q
antifungals that alter cell permeability
A
azoles
polyenes
terbinafine
2
Q
antifungals that block nucleic acid synthesis
A
flucytosine
3
Q
antifungals that disrupt microtubule formation
A
griseofulvin
4
Q
blocks ergosterol synthesis
A
azoles
5
Q
binds to squalene oxidase to block lanosterol and eventual ergosterol synthesis
A
terbinafine
6
Q
WIDEST antifungal spectrum
A
Amphotericin B
7
Q
Potent CYP450 inhibitor affecting phase I of metabolism
A
ketoconazole
8
Q
Azole with good CNS penetrability
A
fluconazole
9
Q
Azole alternative for amphotericin B for cryptococcosis
A
Fluconazole
10
Q
BROADEST spectrum triazole, the only azole with activity against Rhizopus sp. (mucormycosis)
A
Psaconazole
11
Q
CYP450 inducer
A
griseofulvin
