Drugs Affecting the Immunologic System (Part 2)

Question 1

Histamine

Receptors in smooth muscle of vascular system, bronchial tree, digestive tract, heart, and CNS.

a. ) Histamine 1
b. ) Histamine 2

Answer 1

Histamine 1

Question 2

Histamine

Can be given to decrease HCL secretion.

a. ) Histamine 1
b. ) Histamine 2

Answer 2

Histamine 2

Question 3

Histamine

Stimulation results in itching, pain, edema, vasodilation, and bronchoconstriction.

a. ) Histamine 1
b. ) Histamine 2

Answer 3

Histamine 1

Question 4

Histamine

Primarily in the stomach.

a. ) Histamine 1
b. ) Histamine 2

Answer 4

Histamine 2

Question 5

Histamine

Stimulation results in secretion of HCl.

a. ) Histamine 1
b. ) Histamine 2

Answer 5

Histamine 2

Question 6

Used for the treatment of allergies, motion sickness, and insomnia. There are no CNS effects (no drowsiness), and there are no effects on gastric acid production.

a. ) 1^st generation antihistamines
b. ) 2^nd generation antihistamines
c. ) 1^st generation NSAIDs
d. ) 2^nd generation NSAIDs

Answer 6

2^nd generation antihistamines

Question 7

Reduces inflammation without side effects of COX-1 (does not effect stomach lining).

a. ) 1^st generation antihistamines
b. ) 2^nd generation antihistamines
c. ) 1^st generation NSAIDs
d. ) 2^nd generation NSAIDs

Answer 7

2^nd generation NSAIDs

Question 8

Nonselective (blocks both H1 and H2).

a. ) 1^st generation antihistamines
b. ) 2^nd generation antihistamines
c. ) 1^st generation NSAIDs
d. ) 2^nd generation NSAIDs

Answer 8

1^st generation antihistamines

Question 9

Block cyclooxygenase-1 (COX-1-protects stomach linging) and cyclooxygenase-2 (COX-2).

a. ) 1^st generation antihistamines
b. ) 2^nd generation antihistamines
c. ) 1^st generation NSAIDs
d. ) 2^nd generation NSAIDs

Answer 9

1^st generation NSAIDs

Aspirin’s main side effect is GI bleeding.

Tinnitus

Reye’s Syndrome: fat accumulation in brain and liver. Potentially fatal.

Watch for interactions with herbals: Feverfew, garlic, ginseng, and gingko.

Question 10

Selective for H1 only.

a. ) 1^st generation antihistamines
b. ) 2^nd generation antihistamines
c. ) 1^st generation NSAIDs
d. ) 2^nd generation NSAIDs

Answer 10

2^nd generation antihistamines

Question 11

Causes Reye’s syndrome and Tinnitus.

a. ) 1^st generation antihistamines
b. ) 2^nd generation antihistamines
c. ) 1^st generation NSAIDs
d. ) 2^nd generation NSAIDs

Answer 11

1^st generation NSAIDs

Aspirin’s main side effect is GI bleeding.

Tinnitus

Reye’s Syndrome: fat accumulation in brain and liver. Potentially fatal.

Watch for interactions with herbals: Feverfew, garlic, ginseng, and gingko.

Question 12

Contraindicated in patients with dysrhythmias or heart failure. May cause CNS depression.

a. ) 1^st generation antihistamines
b. ) 2^nd generation antihistamines
c. ) 1^st generation NSAIDs
d. ) 2^nd generation NSAIDs

Answer 12

1^st generation antihistamines

Question 13

Glucocorticoids are ________.

It is also important to check for _______.

Answer 13

Glucocorticoids are immunosuppresants.

Accuchecks (increased glucose)

Cushing Syndrome (adrenocortical excess)

Question 14

Glucocorticoids can cause mood changes (teenagers go cray cray), and they can also mask the S/S of infection.

Answer 14

Question 15

For treating fever, you can give _____ to kids, but not _____.

Answer 15

For treating fever, you can give Tylenol to kids, but not Aspirin.

Tylenol = :)

Aspirin = :(

Question 16

Long-term use of _______ will affect Coumadin/Warfarin (increase bleeding times).

Answer 16

Long-term use of antipyretics will affect Coumadin/Warfarin (increase bleeding times).

Question 17

________ mimic the SNS.

Answer 17

Sympathomimetics mimic the SNS.