ANS

Question 1

Acetylcholinesterase inhibitors / cholinesterase inhibitors will _______ acetylcholine.

a. ) increase
b. ) decrease

Answer 1

increase

Question 2

_______ is the drug of choice for bradycardia and cholinergic crisis because it blocks the parasympathetic system.

Answer 2

Atropine

Atropine is an anti-muscarinic / anti-cholinergic

Treatment of anti-muscarinic poisoning = give antidote (physostigmine)

Question 3

Abdominal pain, diarrhea, nausea, vomiting, lacrimation, blurred vision, bronchial hypersecretion due to parasympathetic hyperresponse.

a. ) Muscarinic Crisis
b. ) Cholinergic Crisis
c. ) Myasthenia Gravis
d. ) Myasthenic Crisis
e. ) Nicotinic Crisis

Answer 3

Muscarinic Crisis

Abdominal pain, diarrhea, nausea, vomiting, lacrimation, blurred vision, bronchial hypersecretion due to parasympathetic hyperresponse.

Question 4

An over-stimulation at a neuromuscular junction due to an excess of acetylcholine (ACh), as of a result of the inactivity (perhaps even inhibition) of acetylcholinesterase, caused by nerve gas, in patients with myasthenia gravis who have overdosed on cholinergic agents, or in surgical candidates, due to an excess of cholinesterase inhibitor given to reverse surgical muscle paralysis.

a. ) Muscarinic Crisis
b. ) Cholinergic Crisis
c. ) Myasthenia Gravis
d. ) Myasthenic Crisis
e. ) Nicotinic Crisis

Answer 4

Cholinergic Crisis

An over-stimulation at a neuromuscular junction due to an excess of acetylcholine (ACh), as of a result of the inactivity (perhaps even inhibition) of acetylcholinesterase

Caused by nerve gas, in patients with myasthenia gravis who have overdosed on cholinergic agents, or in surgical candidates, due to an excess of cholinesterase inhibitor given to reverse surgical muscle paralysis.

Question 5

Treated with cholinergic drugs in attempt to decrease muscle weakness. Cholinergic drugs increase aceytcholine which stimulates muscles and decreases muscle weakness. Overdose of this drug, or adverse effects of this drug would result in a cholinergic crisis.

a. ) Muscarinic Crisis
b. ) Cholinergic Crisis
c. ) Myasthenia Gravis
d. ) Myasthenic Crisis
e. ) Nicotinic Crisis

Answer 5

Myasthenia Gravis

Treated with cholinergic drugs in attempt to decrease muscle weakness.

Cholinergic drugs increase aceytcholine which stimulates muscles and decreases muscle weakness.

Overdose of this drug, or adverse effects of this drug would result in a cholinergic crisis.

Question 6

An acute ↑ in requirement for anticholinesterase therapy or refractoriness to therapy, diagnosed by a Tensilon test, with transient ↓ of symptoms.

a. ) Muscarinic Crisis
b. ) Cholinergic Crisis
c. ) Myasthenia Gravis
d. ) Myasthenic Crisis
e. ) Nicotinic Crisis

Answer 6

Myasthenic Crisis

An acute ↑ in requirement for anticholinesterase therapy or refractoriness to therapy, diagnosed by a Tensilon test, with transient ↓ of symptoms.

Question 7

Muscle weakness, fasciculations, cramping and dysphagia, due to over depolarization at the neuromuscular junction.

a. ) Muscarinic Crisis
b. ) Cholinergic Crisis
c. ) Myasthenia Gravis
d. ) Myasthenic Crisis
e. ) Nicotinic Crisis

Answer 7

Nicotinic Crisis

Muscle weakness, fasciculations, cramping and dysphagia, due to over depolarization at the neuromuscular junction.