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PLE SEPTEMBER 2018 > Drug Toxiciy and Antidotes > Flashcards

Drug Toxiciy and Antidotes Flashcards

1
Q

Acetaminophen

A

N-acetylcysteine.

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2
Q

Acid/alkali ingestion

A

Upper endoscopy to evaluate for stricture.

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3
Q

Anticholinesterases, organophosphates

A

Atropine, pralidoxime.

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4
Q

Antimuscarinic/anticholinergic agents

A

Physostigmine.

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5
Q

Arsenic, mercury, gold

A

Succimer, dimercaprol.

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6
Q

β-blockers

A

Glucagon.

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7
Q

Barbiturates (phenobarbital)

A

Urine alkalinization, dialysis, activated charcoal, supportive care.

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8
Q

Benzodiazepines

A

Flumazenil (can precipitate withdrawal, mainly used for acute ingestion).

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9
Q

Black widow bite

A

Calcium gluconate, methocarbamol.

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10
Q

Carbon monoxide

A

100% O2, hyperbaric O2

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11
Q

Copper, arsenic, lead, gold

A

Penicillamine.

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12
Q

Cyanide

A

Hydroxycobalamin, amyl nitrate, sodium nitrate, sodium thiosulfate.

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13
Q

Digitalis

A

Normalize K+ , anti-digitalis Fab.

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14
Q

Heparin

A

Protamine sulfate.

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15
Q

INH

A

Pyridoxine.

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16
Q

Iron salts

A

Deferoxamine.

17
Q

Lead

A

Succimer, CaEDTA, dimercaprol.

18
Q

Methanol, ethylene glycol (antifreeze)

A

EtOH, fomepizole, dialysis, calcium gluconate for ethylene glycol.

19
Q

Methemoglobin

A

Methylene blue.

20
Q

Opioids

A

Naloxone.

21
Q

Salicylates

A

Urine alkalinization, dialysis, activated charcoal.

22
Q

TCAs

A

Sodium bicarbonate for QRS prolongation; diazepam or lorazepam for seizures; cardiac monitor for arrhythmias.

23
Q

Theophylline

A

Activated charcoal. Consider repeat doses.

24
Q

tPA, streptokinase

A

Aminocaproic acid.

25
Q

Warfarin

A

Vitamin K, FFP.

PLE SEPTEMBER 2018 (26 decks)

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