Drug Eruptions Flashcards
Which reaction includes local, itchy wheals surrounded by redness and are immediate? Rarely last more than 24 hours.
Urticarial reaction.
Which reaction is the most frequent type and are macula-papular, usually symmetrical, starting as small, red papules or maculae that converge to form erythmatous plaques? Usually begin on the trunk and mild fever and itching are common, normally gone within two weeks.
Morbilliform eruption.
Which reaction includes sudden onset with lesions appearing symmetrically on distal portions on extremities? Sore throat and malaise are common symptoms.
Erythema multiforme.
Which reaction includes sharply defined, often single red or purple lesions of the skin or mucous membranes? They reoccur at the same spot each time the drug is administered.
Fixed drug eruptions.
Which reaction includes purple maculae and papillae that do not fade on pressure? Most common on legs.
Purpuric eruptions.
Which pattern includes generalized severe redness and scaling of the skin with rapid or insidious onset?
Exfoliative erythroderma.
Which pattern includes skin being red and tender followed by blistering and then large sheets of skin may peel off with gentle pressure?
Toxic epidermal necrolysis.
Which drug reactions are considered toxic heat combined with wind?
Urticarial, morbilliform, and purpuric eruptions.
What is the tx principle for toxic heat combined with wind?
Clear heat from wei and qi levels, cool the blood, and relieve toxicity.
What are the formulas for toxic heat combined with wind?
Yin qiao san and bai hu tang with sheng di, mu dan pi, and chi shao.
Which drug reactions are considered blood heat combined with dampness?
Erythema multiforme and fixed drug eruptions.
What is the tx principle for blood heat combined with dampness?
Clear and transform damp-heat, cool the blood, and relieve toxicity.
What is the formula for blood heat combined with dampness?
Xi jiao di huang tang jia jian.
Which drug eruption is associated with fire toxins sinking?
Early stage toxic epidermal necrolysis.
What is the tx principle for fire toxins sinking?
Clear heat and fire toxins.
What is the formula for fire toxins sinking?
Qing wen bai du yin.