Downs Syndrome / Autism

Question 1

Syndrome associated with abnormal chemotaxis of neutrophils?

Answer 1

Trisomy 21

Chemotaxis is the movement of an organism in response to a chemical stimulus. Somatic cells, bacteria, and other single-cell or multicellular organisms direct their movements according to certain chemicals in their environment.

Question 2

Females with autism have a higher degree of cognitive impairment.

T/F?

Answer 2

True

Females with ASD showed significantly lower overall, verbal, nonverbal cognitive scores as well as reduced language scores.

Question 3

Self-Injurious behavior is common in Autism.

T/F?

Answer 3

True

Self-injurious behaviors (SIBs).

These are behaviors that an individual engages in that may cause physical harm, such as head banging, or self-biting. SIBs are more common in children with ASD than those who are typically developing or have other neurodevelopmental disabilities.

Question 4

Cardiac Defects associated with Trisomy 21?

Answer 4

The most common defects: are

1. Atrioventricular Septal Defect (AVSD)
2. Ventricular Septal Defect (VSD)
3. Persistent Ductus Arteriosus (PDA)
4. Tetralogy of Fallot (TOF)

Question 5

Most common malignancy with Down’s Syndrome?

Answer 5

Leukemia

Question 6

Someone with Down’s Syndrome has how many chromosomes?

Answer 6

47

Normal is 46 total
2 Pairs of 23
Downs as an extra 21 (Trisomy)

Question 7

The primary cause for Periodontitis in Patients with Down syndrome

Answer 7

Defective Neutrophil Chemotaxis