Dna, Rna, And Protein Synthsis Flashcards
What are the essential roles for a substance to be the genetic instructions.
- store genetic instructions
- copy instructions (replication)
- transmit information (transcription)
Chemical Composition of DNA
- Deoxyribose Sugar
- Phosphate Group
- Nitrogenous Base
All three make up nucleotide
Two types of Nitrogenous bases
- Purines: adenine+guanine and possess 2 C+n rings
- Pyrimidines: thymine+cytosine and posses 1 C+n ring.
The building unit for nucleic acids are …… And are …..
Nucleotides and are covalently bonded together.
Scientist who discovered the complementary base pairs
Chargaff
A=
T
G=
C
Chargaff rule states that
A always pairs with T and G always pairs with C
Scientists who identified the shape of DNA
Wilkins and Franklin
Instruments used by Franklin and Wilkins
X-Ray images of DNA crystals
What is the shape of DNA
Helix (spirals)
2 strands of nucleotides exist which means
DNA is referred to as the double helix.
Scientists who developed the model of DNA
Watson and Crick.
The DNA structure consists of 2 strands of
nucleotides that run in opposite directions which are anti-parallel
The 2 strands create a backbone and are composed of
alternating sugar and phosphate.
Nucleotides in the backbone are held together by
covalent bonds
Stands in the middle are held together by
Hydrogen bonds.
Hydrogen bonds allow for the
separation for replication.
A= T because of
two hydrogen bonds.
G=C because of
three hydrogen bonds.
The genetic instructions are dependent on
the exact sequence of bases on each chain.
Copying process required for cell division
Replication
Why is replication essential?
Replication makes sure that each new cell has a complete set of genetic instructions.
Replications occurs in what phase?
The S phase of interphase.
Replication is regulated by
several enzymes in a series of steps.
What is the replication fork?
The point at which two chains separate.
What are the helicases?
The specific enzymes that do the separating of the chains.
How do helicases separate chains?
By breaking the hydrogen bonds between the base pairs.